Evidence map›Paper›PMID 32937915›Full record

ArticlePharmaceutics2020

Cathepsin B-Responsive Liposomes for Controlled Anticancer Drug Delivery in Hep G2 Cells.

Seulgi Lee, Su Jeong Song, Jeil Lee, Tai Hwan Ha, Joon Sig Choi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 46 citations in OpenAlex.

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  9. Recent Progress in Bio-Responsive Drug Delivery Systems for Tumor Therapy.Frontiers in bioengineering and biotechnology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Seulgi LeeDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Korea.
Su Jeong SongDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Korea.
Jeil LeeDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Korea.
Tai Hwan HaBioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.ORCID 0000-0003-0892-3320
Joon Sig ChoiDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-8463-841X
Chungnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) NRF-2018M3A9B5024060 and NRF-2018M3A9B5024068Korea Environmental Industry and Technology Institute No. RE201804085
6 · The paper itself

Abstract

In recent decades, several types of anticancer drugs that inhibit cancer cell growth and cause cell death have been developed for chemotherapeutic application. However, these agents are usually associated with side effects resulting from nonspecific delivery, which may induce cytotoxicity in healthy cells. To reduce the nonspecific delivery issue, nanoparticles have been successfully used for the delivery of anticancer drugs to specific target sites. In this study, a functional polymeric lipid, PEG-GLFG-K(C

Indexed as

cathepsin Bdrug deliveryGLFG peptideliposome

Identifiers

PMID32937915
PMCPMC7558574
OpenAlexW3085569720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.