Evidence map›Paper›PMID 32937858›Full record

ReviewNutrients2020

Dietary Advanced Glycation Endproducts and the Gastrointestinal Tract.

Timme van der Lugt, Antoon Opperhuizen, Aalt Bast, Misha F Vrolijk

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Determination of AGE-CML Level in Commercially Available Sports Bar in Italy.Recent advances in food, nutrition & agriculture · 2025
    Article
  8. Review
  9. Management Effects on Gastrointestinal Disease in Red Wolves (Animals : an open access journal from MDPI · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Molecules (Basel, Switzerland) · 2022
    Article
  15. CaInternational journal of molecular sciences · 2022
    Article
  16. Review
  17. Article
  18. Exposure ofNutrients · 2021
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Timme van der LugtDepartment of Pharmacology and Toxicology, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0003-4487-6410
Antoon OpperhuizenDepartment of Pharmacology and Toxicology, Maastricht University, 6229 ER Maastricht, The Netherlands.
Aalt BastDepartment of Pharmacology and Toxicology, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0002-5383-2789
Misha F VrolijkCampus Venlo, Maastricht University, 5911 BV Venlo, The Netherlands.ORCID 0000-0002-2751-8972
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of inflammatory bowel diseases (IBD) is increasing in the world. The introduction of the Western diet has been suggested as a potential explanation of increased prevalence. The Western diet includes highly processed food products, and often include thermal treatment. During thermal treatment, the Maillard reaction can occur, leading to the formation of dietary advanced glycation endproducts (dAGEs). In this review, different biological effects of dAGEs are discussed, including their digestion, absorption, formation, and degradation in the gastrointestinal tract, with an emphasis on their pro-inflammatory effects. In addition, potential mechanisms in the inflammatory effects of dAGEs are discussed. This review also specifically elaborates on the involvement of the effects of dAGEs in IBD and focuses on evidence regarding the involvement of dAGEs in the symptoms of IBD. Finally, knowledge gaps that still need to be filled are identified.

Indexed as

Dietary ProteinsDiet, WesternGastrointestinal TractGlycation End Products, AdvancedHumansInflammatory Bowel DiseasesMaillard ReactionPrevalenceDietary ProteinsGlycation End Products, Advanceddietary advanced glycation endproductsdigestiongastrointestinal tractinflammationinflammatory bowel disease

Identifiers

PMID32937858
PMCPMC7551018
OpenAlexW3086427337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.