Evidence map›Paper›PMID 32937754›Full record

ReviewInternational journal of molecular sciences2020

Recent Advances in Cell-Based Therapies for Ischemic Stroke.

Satoshi Suda, Chikako Nito, Shoji Yokobori, Yuki Sakamoto, Masataka Nakajima, Kota Sowa, Hirofumi Obinata, Kazuma Sasaki, Sean I Savitz, Kazumi Kimura

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Research progress on optimization ofFrontiers in bioengineering and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Satoshi SudaDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.ORCID 0000-0002-7242-2005
Chikako NitoDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.
Shoji YokoboriDepartment of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8602, Japan.
Yuki SakamotoDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.
Masataka NakajimaDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.
Kota SowaDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.
Hirofumi ObinataDepartment of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8602, Japan.
Kazuma SasakiDepartment of Emergency and Critical Care Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo 113-8602, Japan.
Sean I SavitzInstitute for Stroke and Cerebrovascular Disease, UTHealth, Houston, TX 77030, USA.
Kazumi KimuraDepartment of Neurology, Nippon Medical School, Tokyo 113-8602, Japan.

Funding

JSPS KAKENHI 19K09492
6 · The paper itself

Abstract

Stroke is the most prevalent cardiovascular disease worldwide, and is still one of the leading causes of death and disability. Stem cell-based therapy is actively being investigated as a new potential treatment for certain neurological disorders, including stroke. Various types of cells, including bone marrow mononuclear cells, bone marrow mesenchymal stem cells, dental pulp stem cells, neural stem cells, inducible pluripotent stem cells, and genetically modified stem cells have been found to improve neurological outcomes in animal models of stroke, and there are some ongoing clinical trials assessing their efficacy in humans. In this review, we aim to summarize the recent advances in cell-based therapies to treat stroke.

Indexed as

AnimalsBrain IschemiaCell- and Tissue-Based TherapyHumansIschemic StrokeStem Cellsangiogenesisclinical trialinflammationneurogenesisstem cellstroke

Identifiers

PMID32937754
PMCPMC7555943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.