Evidence map›Paper›PMID 32937495›Full record

ArticleScience advances2020

Synaptic mechanisms for motor variability in a feedforward network.

Guo Zhang, Ke Yu, Tao Wang, Ting-Ting Chen, Wang-Ding Yuan, Fan Yang, Zi-Wei Le, Shi-Qi Guo, Ying-Yu Xue, Song-An Chen and 5 more

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  9. An in vitro analog of learning that food is inedible inLearning & memory (Cold Spring Harbor, N.Y.) · 2023
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  13. Characterization of anFrontiers in pharmacology · 2023
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Guo ZhangState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.ORCID 0000-0002-6828-5968
Ke YuState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.ORCID 0000-0002-6275-9907
Tao WangNational Laboratory of Solid State Microstructures, Department of Physics, Institute for Brain Sciences, and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, Jiangsu 210093, China.ORCID 0000-0003-2846-0474
Ting-Ting ChenState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.ORCID 0000-0001-9520-1259
Wang-Ding YuanState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Fan YangNational Laboratory of Solid State Microstructures, Department of Physics, Institute for Brain Sciences, and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, Jiangsu 210093, China.
Zi-Wei LeState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Shi-Qi GuoState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Ying-Yu XueState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Song-An ChenState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Zhe YangState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China.
Feng LiuNational Laboratory of Solid State Microstructures, Department of Physics, Institute for Brain Sciences, and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, Jiangsu 210093, China. jingj01@live.com fliu@nju.edu.cn.ORCID 0000-0001-9560-8518
Elizabeth C CropperDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Klaudiusz R WeissDepartment of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jian JingState Key Laboratory of Pharmaceutical Biotechnology, Institute for Brain Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, Advanced Institute for Life Sciences, School of Life Sciences, Nanjing University, Nanjing, Jiangsu 210023, China. jingj01@live.com fliu@nju.edu.cn.ORCID 0000-0003-1422-143X

Funding

Neural Basis of Behavioral ArousalR01NS066587 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CROPPER, ELIZABETH C · 2009 to 2023
$5.2M
Neural Basis of Behavioral FlexibilityR01NS070583 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CROPPER, ELIZABETH C, WEISS, KLAUDIUSZ ROBERT · 2010 to 2020
$3.6M
NINDS NIH HHS R01 NS066587
6 · The paper itself

Abstract

Behavioral variability often arises from variable activity in the behavior-generating neural network. The synaptic mechanisms underlying this variability are poorly understood. We show that synaptic noise, in conjunction with weak feedforward excitation, generates variable motor output in the

Identifiers

PMID32937495
PMCPMC7458462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.