Evidence map›Paper›PMID 32937078›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Enrichment Benefits of Risk Algorithms for Pulmonary Arterial Hypertension Clinical Trials.

Jacqueline V Scott, Christine E Garnett, Manreet K Kanwar, Norman L Stockbridge, Raymond L Benza

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. The sine transform is theFrontiers in cardiovascular medicine · 2023
    Article
  9. Article
  10. Risk, Results, and Costs: Optimizing Clinical Trial Efficiency through Prognostic Enrichment.American journal of respiratory and critical care medicine · 2021
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jacqueline V ScottDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.ORCID 0000-0002-0979-712X
Christine E GarnettCenter for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland; and.
Manreet K KanwarCardiovascular Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Norman L StockbridgeCenter for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland; and.
Raymond L BenzaCardiovascular Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
United States Food and Drug Administration · USAllegheny Health Network · US

Funding

PHORA: A Clinical Decision Support Tool for Patients with Pulmonary Arterial HypertensionR01HL134673 · NHLBI · OHIO STATE UNIVERSITY · PI BENZA, RAYMOND LOUIS · 2017 to 2020
$2.8M
NHLBI NIH HHS R01 HL134673
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlgorithmsGuidelines as TopicAdultAgedAged, 80 and overAntihypertensive AgentsClinical Trials as TopicCohort StudiesFamilial Primary Pulmonary HypertensionFemaleHumansMaleMiddle AgedPulmonary Arterial HypertensionRisk AssessmentUnited StatesAntihypertensive Agentsclinical trial enrichmentpulmonary arterial hypertensionrisk score calculator

Identifiers

PMID32937078
PMCPMC7958501
OpenAlexW3086007739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.