Evidence map›Paper›PMID 32936693›Full record

ReviewAmerican journal of men's health

Men and COVID-19: A Pathophysiologic Review.

Martin S Lipsky, Man Hung

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  15. Potential Protection of Pre-Existent Antibodies to Human Coronavirus 229E on COVID-19 Severity.International journal of environmental research and public health · 2021
    Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Martin S LipskyRoseman University of Health Sciences College of Dental Medicine, South Jordan, UT, USA.
Man HungRoseman University of Health Sciences College of Dental Medicine, South Jordan, UT, USA.ORCID 0000-0003-2827-3740
Portland State University · USRoseman University of Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronaviruses are single-stranded ribonucleic acid viruses that can cause illnesses in humans ranging from the common cold to severe respiratory disease and even death.In March 2020, the World Health Organization declared the 2019 novel coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the first pandemic. Compared to women, most countries with available data report that men with COVID-19 have greater disease severity and higher mortality. Lab and animal data indicate that men respond differently to the SARS-CoV-2 infection, offering possible explanations for the epidemiologic observations. The plausible theories underlying these observations include sex-related differences in angiotensin-converting enzyme 2 receptors, immune function, hormones, habits, and coinfection rates.In this review we examine these factors and explore the rationale as to how each may impact COVID-19. Understanding why men are more likely to experience severe disease can help in developing effective treatments, public health policies, and targeted strategies such as early recognition and aggressive testing in subgroups.

Indexed as

Angiotensin-Converting Enzyme 2BiomarkersCoronavirus InfectionsCOVID-19FemaleGenetic MarkersGlobal HealthHumansMalePandemicsPeptidyl-Dipeptidase APneumonia, ViralPrevalenceRisk AssessmentSevere Acute Respiratory SyndromeSex FactorsACE2 protein, humanAngiotensin-Converting Enzyme 2BiomarkersGenetic MarkersPeptidyl-Dipeptidase AcoronavirusCOVID-19crisisMenpandemicpathologypublic healthSAR-CoV-2

Identifiers

PMID32936693
PMCPMC7495118
OpenAlexW3086839004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.