Evidence map›Paper›PMID 32936447›Full record

ArticleJournal of the American Geriatrics Society2020

Conflicting Orders in Physician Orders for Life-Sustaining Treatment Forms.

Robert Y Lee, Matthew E Modes, Seelwan Sathitratanacheewin, Ruth A Engelberg, J Randall Curtis, Erin K Kross

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Healthcare utilization and end-of-life care based on life-sustaining treatment decisions in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Aligning POLST orders with wishes: Time to put evidence into practice.Journal of the American Geriatrics Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Robert Y LeeCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-5535-287X
Matthew E ModesCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.
Seelwan SathitratanacheewinCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.
Ruth A EngelbergCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.
J Randall CurtisCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.
Erin K KrossCambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA.
University of Washington · USChulalongkorn University · TH

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
Palliative Care Research Training GrantT32HL125195 · NHLBI · UNIVERSITY OF WASHINGTON · PI KROSS, ERIN KATHRYN, SHARMA, RASHMI K. · 2015 to 2024
$3.2M
University of Washington Implementation Science Training Program (UW-ISTP)K12K12HL137940 · NHLBI · UNIVERSITY OF WASHINGTON · PI AU, DAVID H, CURTIS, J RANDALL · 2017 to 2021
$2.9M
Goal-discordant care in acute respiratory failure: risk factors and mechanismsF32HL142211 · NHLBI · UNIVERSITY OF WASHINGTON · PI LEE, ROBERT YING-FU · 2018 to 2019
$99k
NCATS NIH HHS UL1 TR002319NHLBI NIH HHS F32 HL142211NHLBI NIH HHS K12 HL137940NHLBI NIH HHS T32 HL007287NHLBI NIH HHS T32 HL125195
6 · The paper itself

Abstract

BACKGROUND/

objectivesMany older persons with chronic illness use Physician Orders for Life-Sustaining Treatment (POLST) to document portable medical orders for emergency care. However, some POLSTs contain combinations of orders that do not translate into a cohesive care plan (eg, cardiopulmonary resuscitation [CPR] without intensive care, or intensive care without antibiotics). This study characterizes the prevalence and predictors of POLSTs with conflicting orders.

designRetrospective cohort study.

settingLarge academic health system.

participantsA total of 3,123 POLST users with chronic life-limiting illness who died between 2010 and 2015 (mean age = 69.7 years). MEASUREMENTS: In a retrospective review of all POLSTs in participants' electronic health records, we describe the prevalence of POLSTs with conflicting orders for cardiac arrest and medical interventions, and use clustered logistic regression to evaluate potential predictors of conflicting orders. We also examine the prevalence of conflicts between POLST orders for antibiotics and artificial nutrition with orders for cardiac arrest or medical interventions.

resultsAmong 3,924 complete POLSTs belonging to 3,123 decedents, 209 (5.3%) POLSTs contained orders to "attempt CPR" paired with orders for "limited interventions" or "comfort measures only"; 745/3169 (23.5%) POLSTs paired orders to restrict antibiotics with orders to deliver non-comfort-only care; and, 170/3098 (5.5%) POLSTs paired orders to withhold artificial nutrition with orders to deliver CPR or intensive care. Among POLSTs with orders to avoid intensive care, orders to attempt CPR were more likely to be present in POLSTs completed earlier in the patient's illness course (adjusted odds ratio = 1.27 per twofold increase in days from POLST to death; 95% confidence interval = 1.18-1.36; P < .001).

conclusionAlthough most POLSTs are actionable by clinicians, 5% had conflicting orders for cardiac arrest and medical interventions, and 24% had one or more conflicts between orders for cardiac arrest, medical interventions, antibiotics, and artificial nutrition. These conflicting orders make implementation of POLST challenging for clinicians in acute care settings.

Indexed as

NegotiatingPhysiciansResuscitation OrdersAdvance DirectivesAgedChronic DiseaseCritical CareFemaleHumansLife Support CareMaleRetrospective Studiesadvance care planninggoals of carehealth policyPOLSTquality improvement

Identifiers

PMID32936447
PMCPMC7744421
OpenAlexW3087597591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.