Evidence map›Paper›PMID 32936318›Full record

SynthesisRheumatology international2020

Kawasaki-like disease in children with COVID-19.

Ummusen Kaya Akca, Selman Kesici, Yasemin Ozsurekci, Hayrettin Hakan Aykan, Ezgi Deniz Batu, Erdal Atalay, Selcan Demir, Erdal Sag, Dogus Vuralli, Benan Bayrakci and 2 more

Open access · bronzeAbstract readCase ReportsSystematic Review
In one paragraph

Synthesis in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. COVID-19 alters human microbiomes: a meta-analysis.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  3. When to test for COVID-19 using real-time reverse transcriptase polymerase chain reaction: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Society for Cardiovascular Magnetic Resonance 2022 Cases of SCMR case series.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Review
  8. Nonhuman primate models of pediatric viral diseases.Frontiers in cellular and infection microbiology · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Global Human Threat: The Potential Synergism between Mercury Intoxication and COVID-19.International journal of environmental research and public health · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ummusen Kaya AkcaDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-0426-9432
Selman KesiciDivision of Pediatric Intensive Care Unit, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0003-4746-6986
Yasemin OzsurekciDivision of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0001-8662-6909
Hayrettin Hakan AykanDivision of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0001-5136-3977
Ezgi Deniz BatuDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0003-1065-2363
Erdal AtalayDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-8974-7121
Selcan DemirDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-4320-8632
Erdal SagDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-6542-2656
Dogus VuralliDivision of Pediatric Endocrinology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-4011-2299
Benan BayrakciDivision of Pediatric Intensive Care Unit, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0003-3307-0948
Yelda BilginerDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-6232-0072
Seza OzenDivision of Pediatric Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey. sezaozen@gmail.com.ORCID 0000-0002-2389-7282
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with Coronavirus disease 2019 (COVID-19) are being reported to have manifestations of hyperinflammatory states and/or Kawasaki-like disease. In this study, we investigated children with typical and atypical Kawasaki disease (KD) likely to be associated with COVID-19. We have reported four children with Kawasaki-like disease probably associated with COVID-19. The clinical features were consistent with incomplete KD in three patients. SARS-CoV-2 RT-PCR was positive in one and the serology was positive in one patient with negative RT-PCR. Corticosteroids, anakinra, intravenous immunoglobulin (IVIG), and acetylsalicylic acid were used in the treatment. Three patients recovered after the treatment while one patient died. The literature review revealed 36 articles describing 320 children with Kawasaki-like disease associated with COVID-19. SARS-CoV-2 RT-PCR was negative in 120 (65.5%) of 183 patients while the serology was positive in 130 (83.8%) of 155 patients. The therapeutic options have included IVIG, acetylsalicylic acid, tocilizumab, anakinra, enoxaparin, and methylprednisolone. Pediatric COVID-19 cases may present with atypical/incomplete Kawasaki-like disease. Thus, pediatricians need to be aware of such atypical presentations resembling KD for early diagnosis of COVID-19.

Indexed as

BetacoronavirusChildChild, PreschoolCoronavirus InfectionsCOVID-19Fatal OutcomeFemaleHumansInfantMaleMucocutaneous Lymph Node SyndromePandemicsPneumonia, ViralSARS-CoV-22019 novel coronavirus diseasesCOVID-19Kawasaki diseaseKawasaki-like syndromeSARS-CoV-2

Identifiers

PMID32936318
PMCPMC7492688
OpenAlexW3087273732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.