Evidence map›Paper›PMID 32935906›Full record

ReviewJournal of separation science2021

Detection challenges in quantitative polymer analysis by liquid chromatography.

Wouter C Knol, Bob W J Pirok, Ron A H Peters

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of separation science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Quantitative Analysis ofMolecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Wouter C KnolAnalytical Chemistry Group, van't Hoff Institute for Molecular Sciences (HIMS), Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-0428-9943
Bob W J PirokAnalytical Chemistry Group, van't Hoff Institute for Molecular Sciences (HIMS), Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-4558-3778
Ron A H PetersAnalytical Chemistry Group, van't Hoff Institute for Molecular Sciences (HIMS), Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands.
Academic Center for Dentistry Amsterdam · NLDSM (Netherlands) · NL

Funding

Agilent Technologies #4354Dutch Research CouncilNederlandse Organisatie voor Wetenschappelijk Onderzoek 731.017.303
6 · The paper itself

Abstract

Accurate quantification of polymer distributions is one of the main challenges in polymer analysis by liquid chromatography. The response of contemporary detectors is typically influenced by compositional features such as molecular weight, chain composition, end groups, and branching. This renders the accurate quantification of complex polymers of which there are no standards available, extremely challenging. Moreover, any (programmed) change in mobile-phase composition may further limit the applicability of detection techniques. Current methods often rely on refractive index detection, which is not accurate when dealing with complex samples as the refractive-index increment is often unknown. We review current and emerging detection methods in liquid chromatography with the aim of identifying detectors, which can be applied to the quantitative analysis of complex polymers.

Indexed as

detectionliquid chromatographypolymersquantification

Identifiers

PMID32935906
PMCPMC7821191
OpenAlexW3086999298

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.