Evidence map›Paper›PMID 32935329›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2021

Early experience with critically ill patients with COVID-19 in Montreal.

Yiorgos Alexandros Cavayas, Alexandre Noël, Veronique Brunette, David Williamson, Anne Julie Frenette, Christine Arsenault, Patrick Bellemare, Colin Lagrenade-Verdant, Soazig LeGuillan, Emilie Levesque and 8 more

Abstract read
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Outcomes of critically ill COVID-19 survivors and caregivers: a case study-centred narrative review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022
    Review
  4. Article
  5. Article
  6. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  7. Re: 'Clinical course and outcomes of critically ill patients with COVID-19 infection: a systematic review - authors' reply'.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Article
  8. Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yiorgos Alexandros CavayasService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada. yiorgos.alexandros.cavayas@umontreal.ca.ORCID http://orcid.org/0000-0001-7664-2104
Alexandre NoëlService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Veronique BrunetteService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
David WilliamsonERESI (Equipe de Recherche En Soins Intensifs), Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal, Montreal, QC, Canada.
Anne Julie FrenetteDépartement de Pharmacie, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Faculté de Pharmacie, Université de Montréal, Montreeal, QC, Canada.
Christine ArsenaultDépartement de Biologie Médicale, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Microbiologie, Université de Montréal, Montreal, QC, Canada.
Patrick BellemareService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Colin Lagrenade-VerdantService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Soazig LeGuillanService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Emilie LevesqueService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Yoan LamarcheService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Marc GiassonService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Philippe RicoService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Yanick BeaulieuService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Pierre MarsolaisService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Karim SerriService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Francis BernardService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.
Martin AlbertService de Soins Intensifs, Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord-de l'île de Montréal, Département de Médecine, Université de Montréal, 5400 Gouin Ouest, Montreal, QC, H4J 1C5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMontreal has been the epicentre of the coronavirus disease (COVID-19) pandemic in Canada. Given the regional disparities in incidence and mortality in the general population, we aimed to describe local characteristics, treatments, and outcomes of critically ill COVID-19 patients in Montreal.

methodsA single-centre retrospective cohort of consecutive adult patients admitted to the intensive care unit (ICU) of Hôpital du Sacré-Coeur de Montréal with confirmed COVID-19 were included.

resultsBetween 20 March and 13 May 2020, 75 patients were admitted, with a median [interquartile range (IQR)] age of 62 [53-72] yr and high rates of obesity (47%), hypertension (67%), and diabetes (37%). Healthcare-related infections were responsible for 35% of cases. The median [IQR] day 1 sequential organ failure assessment score was 6 [3-7]. Invasive mechanical ventilation (IMV) was used in 57% of patients for a median [IQR] of 11 [5-22] days. Patients receiving IMV were characterized by a moderately decreased median [IQR] partial pressure of oxygen:fraction of inspired oxygen (day 1 PaO

conclusionsCharacteristics and outcomes of critically ill patients with COVID-19 in Montreal were similar to those reported in the existing literature. We found an increased physiologic dead space, supporting the hypothesis that pulmonary vascular injury may be central to COVID-19-induced lung damage.

Indexed as

AgedAged, 80 and overCanadaCOVID-19Critical IllnessFemaleHospital MortalityHumansMaleMiddle AgedRespiration, ArtificialRetrospective Studiesacute respiratory distress syndromeCOVID-19intensive caremechanical ventilation

Identifiers

PMID32935329
PMCPMC7491980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.