Evidence map›Paper›PMID 32934956›Full record

ArticleBioMed research international2020

Identification, Validation, and Functional Annotations of Genome-Wide Profile Variation between Melanocytic Nevus and Malignant Melanoma.

Wei Han, Wen-Hao Xu, Jian-Xiong Wang, Jia-Min Hou, Hai-Liang Zhang, Xiao-Yu Zhao, Guo-Liang Shen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Phytochemical Constituents and Derivatives ofInternational journal of molecular sciences · 2023
    Review
  7. Article
  8. Relevance of BRAF Subcellular Localization and Its Interaction withInternational journal of molecular sciences · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei Han *Department of Burn and Plastic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.ORCID https://orcid.org/0000-0002-5096-2246
Wen-Hao Xu *Department of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jian-Xiong Wang *Department of Burn and Plastic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Jia-Min HouDepartment of Burn and Plastic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Hai-Liang ZhangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.ORCID https://orcid.org/0000-0001-8408-7446
Xiao-Yu ZhaoDepartment of Burn and Plastic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.ORCID https://orcid.org/0000-0002-9339-9342
Guo-Liang ShenDepartment of Burn and Plastic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.ORCID https://orcid.org/0000-0003-4665-3501
Soochow University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma (CM) is known as an aggressive malignant cancer; some of which are directly derived from melanocytic nevi, which have been attracting growing attention from the last decades. This study focused on comprehensive identification, validation, and functional annotations of prognostic differentially expressed genes (DEGs) between melanocytic nevus and malignant melanoma in genome-wide profiles. DEGs were obtained using three chip datasets from GEO database to identify after standardization annotation. A total of 73 DEGs were identified as possible candidate prognostic biomarkers between melanocytic nevus and malignant melanoma. In addition, survival curves indicated that six hub genes, including

Indexed as

Molecular Sequence AnnotationDiagnosis, DifferentialGene Expression Regulation, NeoplasticGenome, HumanHumansMelanomaNeoplasm ProteinsNevus, PigmentedOligonucleotide Array Sequence AnalysisNeoplasm Proteins

Identifiers

PMID32934956
PMCPMC7479462
OpenAlexW3081757921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.