Evidence map›Paper›PMID 32934954›Full record

ArticleInternational journal of molecular and cellular medicine2020

Comprehensive Analysis of Zinc Derivatives Pro-proliferative, Anti-Apoptotic and Antimicrobial Effect on Human Fibroblasts and Keratinocytes in a Simulated, Nutrient-deficient Environment

Julian-Dario Rembe, Julia Katharina Boehm, Carolin Fromm-Dornieden, Nina Hauer, Ewa Klara Stuermer

Abstract read
In one paragraph

Article in International journal of molecular and cellular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Antimicrobial ZnGels (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julian-Dario RembeDepartment of Vascular and Endovascular Surgery, Heinrich-Heine-University, Düsseldorf, Germany.
Julia Katharina BoehmInstitute for Research in Operative Medicine (IFOM), Witten/Herdecke University, Cologne, Germany.
Carolin Fromm-DorniedenInstitute for Research in Operative Medicine (IFOM), Witten/Herdecke University, Cologne, Germany.
Nina HauerCenter for Biomedical Education and Research (ZBAF), Witten/Herdecke University, Witten, Germany.
Ewa Klara StuermerDepartment of Vascular Medicine, University Heart Center, Translational Wound Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc as therapeutic agent in skin and wound care has been known for centuries, but its role is controversial and comprehensive investigations in nutrient-deficient environments are lacking. We aimed to provide a broad analysis of different zinc derivatives on proliferation, apoptosis and antimicrobial properties in a simulated nutrient-deficient environment

Indexed as

antimicrobial efficacyapoptosiscell proliferationfibroblastskeratinocytesWound healingzinc

Identifiers

PMID32934954
PMCPMC7489115

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.