Evidence map›Paper›PMID 32934862›Full record

ArticleInternational journal of burns and trauma2020

Cerium nitrate enhances anti-bacterial effects and imparts anti-inflammatory properties to silver dressings in a rat scald burn model.

Li-Wu Qian, Andrea B Fourcaudot, Ping Chen, Kenneth S Brandenburg, Alan J Weaver, Kai P Leung

Open access · greenAbstract read
In one paragraph

Article in International journal of burns and trauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Cerium Nitrate StiffensAdvances in wound care · 2023
    Article
  3. Article
  4. CeOPolymers · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Li-Wu QianDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
Andrea B FourcaudotDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
Ping ChenDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
Kenneth S BrandenburgDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
Alan J WeaverDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
Kai P LeungDivision of Combat Wound Repair, U.S. Army Institute of Surgical Research JBSA-Fort Sam Houston, San Antonio 78234, Texas.
United States Army Institute of Surgical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current commercially available silver-based wound dressings such as silver-nylon have been used as antimicrobial barriers for burn and trauma care in combat conditions for over 10 years. However, these dressings do not stabilize the eschar or reduce its toxicity. Cerium nitrate (CN) solutions have been established clinically to stabilize the eschar by decreasing release of inflammatory mediators from burned tissue thereby allowing delayed excision and grafting. In this report, we tested the extent to which CN imparts CN benefits to silver dressings for temporizing treatments of burn wounds and enhancing anti-bacterial activity. Using a rat full-thickness scald burn model, we showed that CN enhanced the anti-bacterial effects of the tested silver-based dressings (Acticoat™, Mepilex™, and Silverlon

Indexed as

antibacterialanti-inflammatoryburnCerium nitrateescharsilver dressings

Identifiers

PMID32934862
PMCPMC7486562
OpenAlexW3086647004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.