Evidence map›Paper›PMID 32934805›Full record

ArticleF1000Research2020

Effects of paracetamol (acetaminophen) on gene expression and permeability properties of the rat placenta and fetal brain.

Liam M Koehn, Yifan Huang, Mark D Habgood, Kai Kysenius, Peter J Crouch, Katarzyna M Dziegielewska, Norman R Saunders

Open access · goldAbstract read
In one paragraph

Article in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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  13. Paracetamol use in pregnancy: Not as safe as we may think?Acta obstetricia et gynecologica Scandinavica · 2023
    Article
  14. Article
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  16. Review
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  19. Article
  20. Paracetamol (Acetaminophen) and the Developing Brain.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Liam M Koehn *Pharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.
Yifan Huang *Pharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.ORCID 0000-0003-1060-3668
Mark D HabgoodPharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.
Kai KyseniusPharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.
Peter J CrouchPharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.
Katarzyna M DziegielewskaPharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.
Norman R SaundersPharmacology & Therapeutics, University of Melbourne, Parkville, Victoria, 3010, Australia.ORCID 0000-0001-6660-7639
The University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetaminophenAnimalsBlood-Brain BarrierBrainFemaleGene ExpressionInflammationPermeabilityPlacentaPregnancyRatsAcetaminophenAFPIL1βimmune responseinflammationinterleukin-1βpermeabilityplacentatransferα-fetoprotein

Identifiers

PMID32934805
PMCPMC7477648
OpenAlexW3033767767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.