Evidence map›Paper›PMID 32934369›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2021

Acute infusion of angiotensin II regulates organic cation transporters function in the kidney: its impact on the renal dopaminergic system and sodium excretion.

Nicolás M Kouyoumdzian, Natalia L Rukavina Mikusic, Gabriel D Robbesaul, Susana B Gorzalczany, Andrea Carranza, Verónica Trida, Belisario E Fernández, Marcelo R Choi

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Annual reports on hypertension research 2020.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  4. Role of the central renin‑angiotensin system in hypertension (Review).International journal of molecular medicine · 2021
    Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nicolás M KouyoumdzianUniversidad de Buenos Aires. CONICET, Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Buenos Aires, Argentina. nicokouy214@gmail.com.
Natalia L Rukavina MikusicUniversidad de Buenos Aires. CONICET, Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Buenos Aires, Argentina.
Gabriel D RobbesaulUniversidad de Buenos Aires. CONICET, Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Buenos Aires, Argentina.
Susana B GorzalczanyUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Farmacología, Cátedra de Farmacología, Buenos Aires, Argentina.
Andrea CarranzaUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Farmacología, Cátedra de Farmacología, Buenos Aires, Argentina.
Verónica TridaUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Bioquímica Clínica, Cátedra de Bioquímica Clínica, Buenos Aires, Argentina.
Belisario E FernándezInstituto Universitario de Ciencias de la Salud, Fundación H.A. Barceló, Buenos Aires, Argentina.
Marcelo R ChoiUniversidad de Buenos Aires. CONICET, Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Buenos Aires · ARInstituto Universitario de Ciencias de la Salud - Fundación Héctor A. Barceló · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A close relationship between angiotensin II (ANG II) and the renal dopaminergic system (RDS) has been reported. Our aim was to study whether renal dopamine and ANG II can interact to modify renal sodium handling and then to elucidate the related mechanism. Anesthetized male Sprague-Dawley rats were used in experiments. ANG II, exogenous dopamine, and decynium-22 (or D-22, an isocyanine that specifically blocks electrogenic organic cation transporters, OCTs), were infused in vivo for 120 min. We analyzed renal and hemodynamic parameters, renal Na

Indexed as

Angiotensin IICationsKidneyAdenosine TriphosphatasesAnimalsDopamineMaleRatsRats, Sprague-DawleySodiumAdenosine TriphosphatasesAngiotensin IICationsDopamineSodiumAngiotensin IIDopamineK+-ATPaseNa+Organic Cation TransportersSodium

Identifiers

PMID32934369
OpenAlexW3087119404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.