Evidence map›Paper›PMID 32934363›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Blood myo-inositol concentrations in preterm and term infants.

Luc P Brion, Dale L Phelps, Robert M Ward, Tracy L Nolen, N Mikko K Hallman, Abhik Das, Daniel J Zaccaro, M Bethany Ball, Kristi L Watterberg, Ivan D Frantz and 9 more

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 20 institutions in 2 countries.

Luc P BrionDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. luc.brion@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-6139-0132
Dale L PhelpsSchool of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.
Robert M WardDepartment of Pediatrics, Division of Neonatology, University of Utah School of Medicine, Salt Lake City, UT, USA.
Tracy L NolenStatistics and Epidemiology Unit, RTI International, Research Triangle Park, NC, USA.
N Mikko K HallmanPEDEGO Research Center, and MRC Oulu, University of Oulu, and Oulu University Hospital, Oulu, Finland.
Abhik DasStatistics and Epidemiology Unit, RTI International, Rockville, USA.
Daniel J ZaccaroStatistics and Epidemiology Unit, RTI International, Research Triangle Park, NC, USA.
M Bethany BallDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.
Kristi L WatterbergDepartment of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Ivan D FrantzDepartment of Pediatrics, Division of Newborn Medicine, Floating Hospital for Children, Tufts Medical Center, Boston, MA, USA.ORCID http://orcid.org/0000-0002-2200-4286
C Michael CottenDepartment of Pediatrics, Duke University, Durham, NC, USA.
Brenda B PoindexterDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
William OhDepartment of Pediatrics, Women & Infants' Hospital, Brown University, Providence, RI, USA.
Ralph A LugoDepartment of Pharmacy Practice, Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, USA.
Krisa P Van MeursDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.
T Michael O'SheaDepartment of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Kristin M Zaterka-BaxterStatistics and Epidemiology Unit, RTI International, Research Triangle Park, NC, USA.
Rosemary D HigginsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Lucile Packard Children's Hospital · USUniversity of Rochester Medical Center · USYale New Haven Hospital · USRTI International · USBrown University · USDuke University · USSidney & Lois Eskenazi Hospital · USAtrium Health Wake Forest Baptist · USEast Tennessee State University · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USIndiana University School of MedicineNational Institutes of Health · USOulu University Hospital · FISouthwestern Medical Center · USTufts Medical Center · USUniversity of Chicago · USUniversity of Cincinnati · USUniversity of New Mexico · USUniversity of Rochester · USUniversity of Utah · US

Funding

Neonatal Research Network Data Coordinating Center (DCC) 2023-2028U24HD095254 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Abhik Das · 2018 to 2026
$70.2M
Neonatal Research Network Data Coordinating Center (DCC)U10HD036790 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI DAS, ABHIK · 2008 to 2017
$62.3M
YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027904 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LAPTOOK, ABBOT R · 1991 to 2015
$8.7M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027880 · NICHD · STANFORD UNIVERSITY · PI VAN MEURS, KRISA PAGE · 1991 to 2015
$6.1M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027856 · NICHD · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SOKOL, GREGORY M. · 1991 to 2015
$5.9M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD040492 · NICHD · DUKE UNIVERSITY · PI COTTEN, CHARLES MICHAEL · 2001 to 2015
$5.4M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD027871 · NICHD · YALE UNIVERSITY · PI EHRENKRANZ, RICHARD A. · 1991 to 2012
$3.9M
NICHD Neonatal Research Network - Stanford UniversityUG1HD027880 · NICHD · STANFORD UNIVERSITY · PI Valerie Chock · 2016 to 2026
$3.3M
Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal ResearchNetworkUG1HD053089 · NICHD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Janell Fuller, Jessie R. Maxwell · 2016 to 2026
$3.2M
NICHD Cooperative Multicenter Neonatal Research NetworkU10HD053089 · NICHD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WATTERBERG, KRISTI L. · 2006 to 2015
$3.2M
Washington D.C. Collaborative PPRUU10HD045993 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VAN DEN ANKER, JOHANNES NICOLAAS · 2004 to 2009
$2.6M
NCRR NIH HHS UL1 RR024139NICHD NIH HHS U10 HD027856NICHD NIH HHS U10 HD027871NICHD NIH HHS U10 HD027880NICHD NIH HHS U10 HD027904NICHD NIH HHS U10 HD036790NICHD NIH HHS U10 HD037249NICHD NIH HHS U10 HD037261NICHD NIH HHS U10 HD040492NICHD NIH HHS U10 HD040498NICHD NIH HHS U10 HD040521NICHD NIH HHS U10 HD045986NICHD NIH HHS U10 HD045993NICHD NIH HHS U10 HD046000NICHD NIH HHS U10 HD053089NICHD NIH HHS U10 HD053119NICHD NIH HHS U24 HD095254NICHD NIH HHS UG1 HD027880NICHD NIH HHS UG1 HD027904NICHD NIH HHS UG1 HD053089
6 · The paper itself

Abstract

objectiveTo describe relationship between cord blood (representing fetal) myo-inositol concentrations and gestational age (GA) and to determine trends of blood concentrations in enterally and parenterally fed infants from birth to 70 days of age. DESIGN/

methodsSamples were collected in 281 fed or unfed infants born in 2005 and 2006. Myo-inositol concentrations were displayed in scatter plots and analyzed with linear regression models of natural log-transformed values.

resultsIn 441 samples obtained from 281 infants, myo-inositol concentrations varied from nondetectable to 1494 μmol/L. Cord myo-inositol concentrations decreased an estimated 11.9% per week increase in GA. Postnatal myo-inositol concentrations decreased an estimated 14.3% per week increase in postmenstrual age (PMA) and were higher for enterally fed infants compared to unfed infants (51% increase for fed vs. unfed infants).

conclusionsFetal myo-inositol concentrations decreased with increasing GA. Postnatal concentrations decreased with increasing PMA and were higher among enterally fed than unfed infants.

Indexed as

Fetal BloodInositolAdolescentGestational AgeHumansInfantInfant, NewbornInositol

Identifiers

PMID32934363
PMCPMC7889639
OpenAlexW3087169471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.