Evidence map›Paper›PMID 32934246›Full record

ArticleScientific reports2020

Using behavioral rhythms and multi-task learning to predict fine-grained symptoms of schizophrenia.

Vincent W-S Tseng, Akane Sano, Dror Ben-Zeev, Rachel Brian, Andrew T Campbell, Marta Hauser, John M Kane, Emily A Scherer, Rui Wang, Weichen Wang and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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  6. Review
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  8. Article
  9. Beyond Detection: Towards Actionable Sensing Research in Clinical Mental Healthcare.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2024
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  14. Detecting Social Contexts from Mobile Sensing Indicators in Virtual Interactions with Socially Anxious Individuals.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2023
    Article
  15. Article
  16. First-Gen Lens: Assessing Mental Health of First-Generation Students across Their First Year at College Using Mobile Sensing.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vincent W-S Tseng *Information Science, Cornell University, Ithaca, 14850, USA. vincent@infosci.cornell.edu.ORCID http://orcid.org/0000-0002-4824-0615
Akane Sano *Department of Electrical and Computer Engineering, Rice University, Houston, 77005, USA.
Dror Ben-ZeevPsychiatry and Behavioral Sciences, University of Washington, Seattle, 98195, USA.
Rachel BrianPsychiatry and Behavioral Sciences, University of Washington, Seattle, 98195, USA.
Andrew T CampbellComputer Science, Dartmouth College, Hanover, 03755, USA.
Marta HauserVanguard Research Group, New York, USA.
John M KaneDepartment of Psychiatry, The Donald and Barbara School of Medicine at Hofstra/Northwell, Hempstead, 11549, USA.
Emily A SchererBiomedical Data Science Department, Dartmouth Geisel School of Medicine, Hanover, 03755, USA.
Rui WangFacebook, Inc., Menlo Park, USA.
Weichen WangComputer Science, Dartmouth College, Hanover, 03755, USA.
Hongyi WenInformation Science, Cornell University, Ithaca, 14850, USA.
Tanzeem ChoudhuryInformation Science, Cornell University, Ithaca, 14850, USA.

Funding

A New Paradigm for Illness Monitoring and Relapse Prevention in SchizophreniaR01MH103148 · NIMH · DARTMOUTH COLLEGE · PI BEN-ZEEV, DROR · 2013 to 2016
$1.5M
NIMH NIH HHS R01 MH103148NIMH NIH HHS R01MH103148
6 · The paper itself

Abstract

Schizophrenia is a severe and complex psychiatric disorder with heterogeneous and dynamic multi-dimensional symptoms. Behavioral rhythms, such as sleep rhythm, are usually disrupted in people with schizophrenia. As such, behavioral rhythm sensing with smartphones and machine learning can help better understand and predict their symptoms. Our goal is to predict fine-grained symptom changes with interpretable models. We computed rhythm-based features from 61 participants with 6,132 days of data and used multi-task learning to predict their ecological momentary assessment scores for 10 different symptom items. By taking into account both the similarities and differences between different participants and symptoms, our multi-task learning models perform statistically significantly better than the models trained with single-task learning for predicting patients' individual symptom trajectories, such as feeling depressed, social, and calm and hearing voices. We also found different subtypes for each of the symptoms by applying unsupervised clustering to the feature weights in the models. Taken together, compared to the features used in the previous studies, our rhythm features not only improved models' prediction accuracy but also provided better interpretability for how patients' behavioral rhythms and the rhythms of their environments influence their symptom conditions. This will enable both the patients and clinicians to monitor how these factors affect a patient's condition and how to mitigate the influence of these factors. As such, we envision that our solution allows early detection and early intervention before a patient's condition starts deteriorating without requiring extra effort from patients and clinicians.

Indexed as

AdolescentBehaviorCluster AnalysisFemaleHumansLearningMachine LearningMaleSchizophrenia

Identifiers

PMID32934246
PMCPMC7492221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.