Evidence map›Paper›PMID 32934095›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2020

Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA

Elif Engin, Maksim Sigal, Dietmar Benke, Anja Zeller, Uwe Rudolph

Open access · diamondAbstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genetics and Molecular Biology of Memory Suppression.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  7. Article
  8. GABATrends in pharmacological sciences · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Acid Sphingomyelinase Is a Modulator of Contextual Fear.International journal of molecular sciences · 2022
    Article
  14. GABAFrontiers in psychiatry · 2022
    Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Elif EnginLaboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, Massachusetts 02478, USA.
Maksim SigalLaboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, Massachusetts 02478, USA.
Dietmar BenkeInstitute of Pharmacology and Toxicology, University of Zurich, CH-8057 Zurich, Switzerland.
Anja ZellerInstitute of Pharmacology and Toxicology, University of Zurich, CH-8057 Zurich, Switzerland.
Uwe RudolphLaboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, Massachusetts 02478, USA.
McLean Hospital · USUniversity of Zurich · CHHarvard University · US

Funding

Regional actions of general anesthetics in inhibitory hippocampal networksR01GM086448 · NIGMS · MCLEAN HOSPITAL · PI RUDOLPH, UWE · 2009 to 2012
$1.9M
Cellular mechanisms for age-related cognitive dysfunction and its pharmacological reversal: a strategy towards prevention and treatment of postoperative cognitive deficits in elderly patientsR01GM128183 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI RUDOLPH, UWE · 2019 to 2022
$1.6M
Intrahippocampal dynamics underlying cognitive rigidityK01MH107787 · NIMH · MCLEAN HOSPITAL · PI ENGIN, ELIF · 2016 to 2019
$696k
NIGMS NIH HHS R01 GM086448NIGMS NIH HHS R01 GM128183NIMH NIH HHS K01 MH107787
6 · The paper itself

Abstract

Reduction in the expression or function of α5-subunit-containing GABA

Indexed as

AnimalsCA1 Region, HippocampalConditioning, ClassicalMaleMemoryMice, Inbred C57BLMice, KnockoutMorris Water Maze TestReceptors, GABA-AGabra5 protein, mouseReceptors, GABA-A

Identifiers

PMID32934095
PMCPMC7497110
OpenAlexW3087222099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.