Evidence map›Paper›PMID 32934083›Full record

ArticlemBio2020

ExPortal and the LiaFSR Regulatory System Coordinate the Response to Cell Membrane Stress in Streptococcus pyogenes.

Yibin Lin, Misu A Sanson, Luis Alberto Vega, Brittany Shah, Shrijana Regmi, M Belen Cubria, Anthony R Flores

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. EmergentInfection and immunity · 2024
    Article
  6. Article
  7. Article
  8. The Dlt and LiaFSR systems derepress SpeB production independently in theFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yibin LinDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Misu A SansonDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Luis Alberto VegaDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Brittany ShahDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Shrijana RegmiDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
M Belen CubriaDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Anthony R FloresDivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, Texas, USA anthony.r.flores@uth.tmc.edu.ORCID 0000-0002-6402-4269
The University of Texas Health Science Center at Houston · US

Funding

Contribution of LiaFSR to pathogenesis and carriage of group A StreptococcusR01AI125216 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FLORES, ANTHONY RICHARD · 2017 to 2021
$1.9M
Texas Medical Center Training Program in Antimicrobial ResistanceT32AI141349 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A · 2019 to 2023
$1.3M
NIAID NIH HHS R01 AI125216NIAID NIH HHS T32 AI141349
6 · The paper itself

Abstract

LiaFSR is a gene regulatory system important for response to cell membrane stress in Gram-positive bacteria but is minimally studied in the important human pathogen group A

Indexed as

Gene Expression Regulation, BacterialStress, PhysiologicalAnti-Bacterial AgentsBacterial ProteinsCell MembraneHumansProtein TransportStreptococcus pyogenesAnti-Bacterial AgentsBacterial Proteinscell envelope stressExPortalgroup A streptococcusLiaFSRmembrane microdomaintwo-component regulatory systems

Identifiers

PMID32934083
PMCPMC7492735
OpenAlexW3085641283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.