ArticleClinical medicine (London, England)2020
Clinical presentation and outcomes of solitary plasmacytoma in a tertiary hospital in the UK.
Article in Clinical medicine (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- International Myeloma Working Group Recommendations for the Diagnosis and Management of Solitary Plasmacytomas.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026Guideline
- Solitary plasmacytoma: single-institution experience, and systematic review and meta-analysis of clinical outcomes.Blood advances · 2025Pooled it
- Solitary Pancreatic Extramedullary Plasmacytoma Diagnosed Through Endoscopic Ultrasound-Guided Fine-Needle Biopsy-The Role of Endoscopic Diagnosis and Multidisciplinary Approach: A Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Extramedullary plasmacytoma of the tibial nerve: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Intradural extramedullary solitary plasmacytoma originating in the cervical spine in the setting of refractory multiple myeloma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Preoperative embolization of a solitary bone plasmacytoma of the proximal humerus.Radiology case reports · 2024Article
- Posttreatment Persistence of Monoclonal Protein on Immunofixation Electrophoresis but Absence on Serum Protein Electrophoresis in a Case of Solitary Bone Plasmacytoma.Journal of laboratory physicians · 2023Article
- Posterior Mediastinum Plasmocytoma: An Infrequent Location.Open respiratory archivesArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary plasmacytoma is a rare localised neoplasm of monoclonal plasma cells. The standard treatment involves radical radiotherapy; however, a significant proportion of patients subsequently develop multiple myeloma. In this study, we evaluate the outcomes of solitary plasmacytoma in a retrospective cohort of patients treated in a single tertiary centre.The case records of plasmacytoma patients treated in a 15-year period were analysed and retrospectively followed up from the date of diagnosis. Thirty-four cases met the inclusion criteria; 27 (79%) solitary plasmacytoma of bone (SBP) and 7 (21%) extramedullary plasmacytoma (EMP). The thoracic vertebrae were the commonest sites for SBP while EMP occurred most frequently in the upper airway. Pain and spinal cord compression were the most frequent symptoms. A paraprotein was detectable in 18 (53%) patients. Over a median follow-up of 48 months, 13 (38%) developed multiple myeloma. The 5- and 10-year survival rates were 80% and 56%, respectively; median progression-free survival was 77 months. Four patients (12%) developed a second malignancy.Progression to multiple myeloma remains a formidable challenge in the management of solitary plasmacytoma, hence adjunct therapies are needed.
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