Evidence map›Paper›PMID 32934044›Full record

ReviewClinical medicine (London, England)2020

Modulating the gut-liver axis and the pivotal role of the faecal microbiome in cirrhosis.

Charlotte Woodhouse, Arjuna Singanayagam, Vishal C Patel

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical medicine (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Charlotte WoodhouseKing's College London, London, UK and King's College Hospital NHS Foundation Trust, London, UK.
Arjuna SinganayagamSt George's University Hospitals NHS Foundation Trust, London, UK and senior clinical lecturer, St George's University of London, London, UK.
Vishal C PatelKing's College Hospital NHS Foundation Trust, London, UK, honorary senior lecturer, King's College London, London, UK and principal investigator, Institute of Hepatology, Foundation for Liver Research, London, UK vish.patel@kcl.ac.uk.
King's College Hospital NHS Foundation Trust · GBSt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaDysbiosisHumansLiver Cirrhosiscirrhosisdysbiosisfaecal microbial transplantationgut–liver axisMicrobiota

Identifiers

PMID32934044
PMCPMC7539737
OpenAlexW3085450888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.