Evidence map›Paper›PMID 32933181›Full record

ArticleNutrients2020

Effects of Human Milk Oligosaccharides on the Adult Gut Microbiota and Barrier Function.

Tanja Šuligoj, Louise Kristine Vigsnæs, Pieter Van den Abbeele, Athanasia Apostolou, Katia Karalis, George M Savva, Bruce McConnell, Nathalie Juge

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 160 citations in OpenAlex.

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  11. Identification of a novel β-1,4-galactosyltransferase fromSynthetic and systems biotechnology · 2026
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Tanja ŠuligojQuadram Institute Bioscience, Gut Microbes and Health Institute Strategic Programme, Norwich Research Park, Norwich NR4 7UQ, UK.
Louise Kristine VigsnæsGlycom A/S, Kogle Allé 4, DK-2970 Hørsholm, Denmark.
Pieter Van den AbbeeleProdigest Bv, B-9052 Gent, Belgium.
Athanasia ApostolouEmulate Inc., 27 Drydock Ave, Boston, MA 02210, USA.
Katia KaralisEmulate Inc., 27 Drydock Ave, Boston, MA 02210, USA.
George M SavvaQuadram Institute Bioscience, Core Sciences Resources, Norwich Research Park, Norwich NR5 7UQ, UK.
Bruce McConnellGlycom A/S, Kogle Allé 4, DK-2970 Hørsholm, Denmark.
Nathalie JugeQuadram Institute Bioscience, Gut Microbes and Health Institute Strategic Programme, Norwich Research Park, Norwich NR4 7UQ, UK.
Norwich Research Park · GBEmulate (United States) · USNational and Kapodistrian University of Athens · GRProDigest (Belgium) · BE

Funding

Biotechnology and Biological Sciences Research Council BB/CCG1860/1Biotechnology and Biological Sciences Research Council BB/R012490/1Biotechnology and Biological Sciences Research Council BBS/E/F/00044452Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10356
6 · The paper itself

Abstract

Human milk oligosaccharides (HMOs) shape the gut microbiota in infants by selectively stimulating the growth of bifidobacteria. Here, we investigated the impact of HMOs on adult gut microbiota and gut barrier function using the Simulator of the Human Intestinal Microbial Ecosystem (SHIME

Indexed as

BifidobacteriumButyric AcidCaco-2 CellsClaudinsColonEnzyme-Linked Immunosorbent AssayFermentationGastrointestinal MicrobiomeHumansImmunityInfantInterleukin-6Milk, HumanOligosaccharidesTight JunctionsTrisaccharides2'-fucosyllactoseButyric Acidclaudin 8ClaudinsInterleukin-6lacto-N-neotetraoseOligosaccharidesTrisaccharidesadult gut microbiotagut barrier functiongut-on-chipshuman milk oligosaccharidesSHIME®

Identifiers

PMID32933181
PMCPMC7551690
OpenAlexW3084990525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.