Evidence map›Paper›PMID 32933144›Full record

ArticlePharmaceutics2020

Phytol-Loaded Solid Lipid Nanoparticles as a Novel Anticandidal Nanobiotechnological Approach.

Tábata L C Lima, Luanda B F C Souza, Lannya C S Tavares-Pessoa, Alaine M Dos Santos-Silva, Rômulo S Cavalcante, Raimundo F de Araújo-Júnior, Alianda M Cornélio, Matheus F Fernandes-Pedrosa, Guilherme Maranhão Chaves, Arnóbio Antônio da Silva-Júnior

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
  6. Review
  7. Solid lipid nanoparticles, an effective carrier for classical antifungal drugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tábata L C LimaLaboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Luanda B F C SouzaDepartment of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte (UFRN), Gal, Gustavo Cordeiro de Faria, S/N, Petrópolis, Natal-RN 59084-100, Brazil.
Lannya C S Tavares-PessoaLaboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Alaine M Dos Santos-SilvaLaboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.ORCID 0000-0002-3010-421X
Rômulo S CavalcanteDepartment of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Raimundo F de Araújo-JúniorDepartment of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Alianda M CornélioDepartment of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Matheus F Fernandes-PedrosaLaboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Guilherme Maranhão ChavesDepartment of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte (UFRN), Gal, Gustavo Cordeiro de Faria, S/N, Petrópolis, Natal-RN 59084-100, Brazil.
Arnóbio Antônio da Silva-JúniorLaboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Universidade Federal do Rio Grande do Norte · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 308382/2017-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 436051/2018-4Coordenação de Aperfeiçoamento de Pessoal de Nível Superior code:001
6 · The paper itself

Abstract

Phytol is a diterpene alcohol and can be found as a product of the metabolism of chlorophyll in plants. This compound has been explored as a potential antimicrobial agent, but it is insoluble in water. In this study, we describe a novel approach for an interesting anticandidal drug delivery system containing phytol. Different formulations of phytol-loaded solid lipid nanoparticles (SLN) were designed and tested using a natural lipid, 1,3-distearyl-2-oleyl-glycerol (TG1). Different compositions were considered to obtain three formulations with 1:10, 1:5, and 1:3

Indexed as

1,3-distearyl-2-oleyl-glycerol (TG1)anticandidal activityCandida spp.phytolsolid lipid nanoparticles

Identifiers

PMID32933144
PMCPMC7558427
OpenAlexW3085316272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.