Evidence map›Paper›PMID 32933135›Full record

ArticleInternational journal of molecular sciences2020

Insights into the Selectivity Mechanisms of Grapevine NIP Aquaporins.

Farzana Sabir, Antonella Di Pizio, Maria C Loureiro-Dias, Angela Casini, Graça Soveral, Catarina Prista

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Farzana SabirLinking Landscape, Environment, Agriculture and Food (LEAF), Departmento de Recursos Biológicos, Ambiente e Território (DRAT), Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017 Lisbon, Portugal.ORCID 0000-0002-0181-989X
Antonella Di PizioLeibniz-Institute for Food Systems Biology at the Technical University of Munich, Lise-Meitner-Str. 34, 85354 Freising, Germany.ORCID 0000-0002-8520-5165
Maria C Loureiro-DiasLinking Landscape, Environment, Agriculture and Food (LEAF), Departmento de Recursos Biológicos, Ambiente e Território (DRAT), Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017 Lisbon, Portugal.
Angela CasiniDepartment of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85748 München, Germany.ORCID 0000-0003-1599-9542
Graça SoveralResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0001-8487-110X
Catarina PristaLinking Landscape, Environment, Agriculture and Food (LEAF), Departmento de Recursos Biológicos, Ambiente e Território (DRAT), Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017 Lisbon, Portugal.ORCID 0000-0001-9307-1905
University of Lisbon · PTLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DETechnical University of Munich · DE

Funding

Fundação para a Ciência e a Tecnologia DL 57/2016/CP1382/CT0012, and SFRH/BPD/89427/2012, UID/AGR/04129/2020 (LEAF) and UID/DTP/04138 /2019 (i.Med)
6 · The paper itself

Abstract

Nodulin 26-like intrinsic proteins (NIPs) of the plant aquaporin family majorly facilitate the transport of physiologically relevant solutes. The present study intended to investigate how substrate selectivity in grapevine NIPs is influenced by the aromatic/arginine (ar/R) selectivity filter within the pore and the possible underlying mechanisms. A mutational approach was used to interchange the ar/R residues between grapevine NIPs (VvTnNIP1;1 with VvTnNIP6;1, and VvTnNIP2;1 with VvTnNIP5;1). Their functional characterization by stopped-flow spectroscopy in

Indexed as

Amino Acid SequenceAquaporinsArabidopsis ProteinsBiological TransportGlycerolHydrophobic and Hydrophilic InteractionsMembrane ProteinsMutationPermeabilityPlant ProteinsSaccharomyces cerevisiaeVitisAquaporinsArabidopsis ProteinsGlycerolMembrane ProteinsnodulinPlant Proteinsar/R selectivity filtergrapevinehomology modelingnodulin 26-like intrinsic proteinssite-directed mutagenesissubstrate selectivity

Identifiers

PMID32933135
PMCPMC7576499
OpenAlexW3085369753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.