Evidence map›Paper›PMID 32933098›Full record

ArticleInternational journal of molecular sciences2020

Relative and Absolute Quantification of Aberrant and Normal Splice Variants in

Petros Patsali, Panayiota Papasavva, Soteroulla Christou, Maria Sitarou, Michael N Antoniou, Carsten W Lederer, Marina Kleanthous

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Petros PatsaliDepartment of Molecular Genetics Thalassaemia, The Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.ORCID 0000-0001-8287-6724
Panayiota PapasavvaDepartment of Molecular Genetics Thalassaemia, The Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.
Soteroulla ChristouThalassaemia Clinic Nicosia, Ministry of Health, Nicosia 1474, Cyprus.
Maria SitarouThalassaemia Clinic Larnaca, Ministry of Health, Larnaca 6301, Cyprus.
Michael N AntoniouDepartment of Medical and Molecular Genetics, King's College London, London SE1 9RT, UK.ORCID 0000-0002-3185-5314
Carsten W LedererDepartment of Molecular Genetics Thalassaemia, The Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.ORCID 0000-0003-3920-9584
Marina KleanthousDepartment of Molecular Genetics Thalassaemia, The Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.
Cyprus Institute of Neurology and Genetics · CYKing's College London · GBLarnaca College · CYMinistry of Health · CY

Funding

Research and Innovation Foundation of Cyprus EXCELLENCE/1216/0092Research and Innovation Foundation of Cyprus ΥΓΕΙΑ/ΒΙΟΣ/0311(ΒΕ)/20Seventh Framework Programme 306201 (THALAMOSS)
6 · The paper itself

Abstract

The β-thalassemias are an increasing challenge to health systems worldwide, caused by absent or reduced β-globin (HBB) production. Of particular frequency in many Western countries is

Indexed as

Alternative Splicingbeta-Globinsbeta-ThalassemiaCells, CulturedHumansMutationRNA, Messengerbeta-GlobinsRNA, Messengerabsolute quantificationduplex quantitative PCRsplice defectsplicingtranscript variantsβ-thalassemia

Identifiers

PMID32933098
PMCPMC7555009
OpenAlexW3086658224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.