ArticleNutrients2020
Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effects of Quinoa (Chenopodium quinoa) on inflammatory mediators: a systematic review of preclinical studies.Inflammopharmacology · 2023Pooled it
- Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health.Nutrients · 2022Pooled it
- Bioactive Peptides from Quinoa (Nutrients · 2025Article
- Multiple benefits of herbs: Polygonaceae species in veterinary pharmacology and livestock nutrition.Veterinary and animal science · 2025Review
- Harnessing the Potential of Quinoa: Nutritional Profiling, Bioactive Components, and Implications for Health Promotion.Antioxidants (Basel, Switzerland) · 2024Review
- Grains in a Modern Time: A Comprehensive Review of Compositions and Understanding Their Role in Type 2 Diabetes and Cancer.Foods (Basel, Switzerland) · 2024Review
- Hepatoprotective efficacy of quinoa seed extract against CClFood science & nutrition · 2024Article
- Therapeutic effects of intermittent fasting on high-fat, high-fructose diet; involvement of jejunal aquaporin 1, 3, and 7.Heliyon · 2024Article
- Progress in research on the effects of quinoa (Frontiers in nutrition · 2024Review
- Quinoa (Food science & nutrition · 2023Article
- Nutritional and bioactive characteristics of buckwheat, and its potential for developing gluten-free products: An updated overview.Food science & nutrition · 2023Review
- Article
- The Beneficial Effect of Coarse Cereals on Chronic Diseases through Regulating Gut Microbiota.Foods (Basel, Switzerland) · 2021Review
- Botany, Nutritional Value, Phytochemical Composition and Biological Activities of Quinoa.Plants (Basel, Switzerland) · 2021Review
- Breeding Buckwheat for Increased Levels and Improved Quality of Protein.Plants (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 4 countries.
Funding
Abstract
In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study of twenty-eight growing male Wistar rats was conducted to investigate the effects of quinoa (QU) and buckwheat (BK) protein-rich flours on the growth parameters, intestinal microbial activity, plasma lipid profile, and inflammatory markers. The biological value of protein and body weight gain were considerably increased in the QU and BK groups compared with those in the soy protein isolate group. Moreover, both flours increased the microbial activity of α-glucosidase, β-glucosidase, and α-galactosidase and the concentration of short-chain fatty acids in the caecum. The studied flours favourably reduced the plasma total cholesterol and LDL cholesterol. In rats fed a diet with QU, elevated levels of plasma interleukin 6 and alanine transaminase were observed. The effect of QU on inflammatory markers may be related to the increased expression of aryl hydrocarbon receptor in the liver and to the decreased level of plasma albumin. In conclusion, quinoa and buckwheat protein-rich flours are valuable sources of proteins that favourably affect growth parameters, gut metabolism, and blood lipid profile in rats; however, only the buckwheat flour has no effect on inflammatory processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.