Evidence map›Paper›PMID 32932925›Full record

ReviewCancers2020

Recent Progress in the Systemic Treatment of Advanced/Metastatic Cholangiocarcinoma.

Raluca Maria Fostea, Elisa Fontana, Gonzalo Torga, Hendrik-Tobias Arkenau

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. [Emphasis on the treatment of biliary liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Horizons on the Therapy of Biliary Tract Cancers: A State-of-the-art Review.Journal of clinical and translational hepatology · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Frontiers in oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raluca Maria FosteaDrug Development Unit, Sarah Cannon Research Institute UK, 93 Harley Street, Marylebone, London W1G 6AD, UK.
Elisa FontanaDrug Development Unit, Sarah Cannon Research Institute UK, 93 Harley Street, Marylebone, London W1G 6AD, UK.ORCID 0000-0002-4991-9355
Gonzalo TorgaDrug Development Unit, Sarah Cannon Research Institute UK, 93 Harley Street, Marylebone, London W1G 6AD, UK.ORCID 0000-0002-6401-5127
Hendrik-Tobias ArkenauDrug Development Unit, Sarah Cannon Research Institute UK, 93 Harley Street, Marylebone, London W1G 6AD, UK.ORCID 0000-0002-2015-1549
Sarah Cannon Research Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinomas (CCAs) comprise of a heterogeneous group of cancers arising in the biliary tract (intrahepatic or iCCA, perihilar or pCCA and distal or dCCA; the latter are known under the collective term of eCCA), each subtype having its own particularities in carcinogenesis, management and prognosis. The increasing incidence in recent decades, limited treatment options and high mortality rates, even in the early stages, have led to an imperious need for more in-depth understanding and development of tailored treatments for this type of aggressive tumour. The wide use of molecular profiling has increased the understanding of biology and identified key molecular drivers, for example,

Indexed as

biliary tract cancerscholangiocarcinomadriver mutationsimmunotherapymolecular profilingtargeted therapy

Identifiers

PMID32932925
PMCPMC7565778
OpenAlexW3085296213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.