ReviewBiology2020
Cnidarian Immunity and the Repertoire of Defense Mechanisms in Anthozoans.
Review in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 62 citations in OpenAlex.
- SpEchinoidin, a C-type lectin and a member of an expanded CTL family, is up-regulated by phagocytes in sea urchins responding to immune challenge.Developmental and comparative immunology · 2026Article
- Unique Transcriptional Responses by the Sea Anemone Nematostella vectensis to Individual Bacteria: Roles for Bacterial Species, Secreted Products and the Microbiome.Molecular ecology · 2026Article
- Thermal Stress-Induced Alterations to Oxylipin Signal Receptors in the Cnidarian-Dinoflagellate Symbiosis.Environmental microbiology · 2026Article
- Coral larvae have unique transcriptomic responses to pathogenic and probiotic bacteria.Coral reefs (Online) · 2026Article
- Immunity: defense against infections essential for all living organisms.Frontiers in immunology · 2026Review
- Nutrient-rich environments drive microbiome restructuring and mucus shedding in a coastal cnidarian.Frontiers in microbiology · 2026Article
- An updated and spatially validated somatic single-cell atlas of Hydractinia symbiolongicarpus.BMC genomics · 2025Article
- Investigating the evolution and features of regeneration using cnidarians.Integrative and comparative biology · 2025Review
- Anthozoan Chemical Defenses: Integrating Compounds, Enzymatic Activities, and Omics-Based Discoveries.International journal of molecular sciences · 2025Review
- An updated and spatially validated somatic single-cell atlas ofbioRxiv : the preprint server for biology · 2025Article
- Exploring different methods of Exaiptasia diaphana infection to follow Vibrio parahaemolyticus dissemination in the whole animal.BMC microbiology · 2025Article
- The Chromosome-level Genome of the Ctenophore Mnemiopsis leidyi A. Agassiz, 1865 Reveals a Unique Immune Gene Repertoire.Genome biology and evolution · 2025Article
- Dose-dependent interaction of parasites with tiers of host defense predicts "wormholes" that prolong infection at intermediate inoculum sizes.PLoS computational biology · 2024Article
- Structural and Evolutionary Relationships of Melanin Cascade Proteins in Cnidarian Innate Immunity.Integrative and comparative biology · 2024Article
- Discovery of deep-sea coral symbionts from a novel clade of marine bacteria with severely reduced genomes.Nature communications · 2024Article
- Prior heat stress increases pathogen susceptibility in the model cnidarian Exaiptasia diaphana.Communications biology · 2024Article
- Global warming-related response after bacterial challenge in Astroides calycularis, a Mediterranean thermophilic coral.Scientific reports · 2024Article
- Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis.Microbiome · 2024Article
- Phenotypic and Functional Heterogeneity of Monocytes and Macrophages.International journal of molecular sciences · 2023Article
- Pervasive tandem duplications and convergent evolution shape coral genomes.Genome biology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Anthozoa is the most specious class of the phylum Cnidaria that is phylogenetically basal within the Metazoa. It is an interesting group for studying the evolution of mutualisms and immunity, for despite their morphological simplicity, Anthozoans are unexpectedly immunologically complex, with large genomes and gene families similar to those of the Bilateria. Evidence indicates that the Anthozoan innate immune system is not only involved in the disruption of harmful microorganisms, but is also crucial in structuring tissue-associated microbial communities that are essential components of the cnidarian holobiont and useful to the animal's health for several functions including metabolism, immune defense, development, and behavior. Here, we report on the current state of the art of Anthozoan immunity. Like other invertebrates, Anthozoans possess immune mechanisms based on self/non-self-recognition. Although lacking adaptive immunity, they use a diverse repertoire of immune receptor signaling pathways (PRRs) to recognize a broad array of conserved microorganism-associated molecular patterns (MAMP). The intracellular signaling cascades lead to gene transcription up to endpoints of release of molecules that kill the pathogens, defend the self by maintaining homeostasis, and modulate the wound repair process. The cells play a fundamental role in immunity, as they display phagocytic activities and secrete mucus, which acts as a physicochemical barrier preventing or slowing down the proliferation of potential invaders. Finally, we describe the current state of knowledge of some immune effectors in Anthozoan species, including the potential role of toxins and the inflammatory response in the Mediterranean Anthozoan
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.