Evidence map›Paper›PMID 32932807›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Characterization of Commercial Metal Oxide Nanomaterials: Crystalline Phase, Particle Size and Specific Surface Area.

Michael Bushell, Suzanne Beauchemin, Filip Kunc, David Gardner, Jeffrey Ovens, Floyd Toll, David Kennedy, Kathy Nguyen, Djordje Vladisavljevic, Pat E Rasmussen and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. High-performance SrO-CoRSC advances · 2026
    Article
  3. Review
  4. Article
  5. Journal of proteome research · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. RSC advances · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael BushellMetrology Research Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.
Suzanne BeaucheminHealth Canada, Environmental Health Research Science Bureau, 251 Sir Frederick Banting Driveway, Ottawa, ON K1A 0K9, Canada.
Filip KuncMetrology Research Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.
David GardnerX-ray Core Facility, University of Ottawa, STEM Complex, 150 Louis Pasteur, Ottawa, ON K1N 6N5, Canada.
Jeffrey OvensX-ray Core Facility, University of Ottawa, STEM Complex, 150 Louis Pasteur, Ottawa, ON K1N 6N5, Canada.
Floyd TollEnergy Mining & Environment Research Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.
David KennedyMetrology Research Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.
Kathy NguyenHealth Canada, New Substances Assessment Control Bureau, 269 Laurier Avenue West, Ottawa, ON K1A 0K9, Canada.
Djordje VladisavljevicHealth Canada, New Substances Assessment Control Bureau, 269 Laurier Avenue West, Ottawa, ON K1A 0K9, Canada.
Pat E RasmussenHealth Canada, Environmental Health Research Science Bureau, 251 Sir Frederick Banting Driveway, Ottawa, ON K1A 0K9, Canada.ORCID 0000-0001-6748-4255
Linda J JohnstonMetrology Research Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.ORCID 0000-0002-9136-4920

Funding

Health Canada N/A
6 · The paper itself

Abstract

Physical chemical characterization of nanomaterials is critical to assessing quality control during production, evaluating the impact of material properties on human health and the environment, and developing regulatory frameworks for their use. We have investigated a set of 29 nanomaterials from four metal oxide families (aluminum, copper, titanium and zinc) with a focus on the measurands that are important for the basic characterization of dry nanomaterials and the determination of the dose metrics for nanotoxicology. These include crystalline phase and crystallite size, measured by powder X-ray diffraction, particle shape and size distributions from transmission electron microscopy, and specific surface area, measured by gas adsorption. The results are compared to the nominal data provided by the manufacturer, where available. While the crystalline phase data are generally reliable, data on minor components that may impact toxicity is often lacking. The crystal and particle size data highlight the issues in obtaining size measurements of materials with broad size distributions and significant levels of aggregation, and indicate that reliance on nominal values provided by the manufacturer is frequently inadequate for toxicological studies aimed at identifying differences between nanoforms. The data will be used for the development of models and strategies for grouping and read-across to support regulatory human health and environmental assessments of metal oxide nanomaterials.

Indexed as

crystalline phasemetal oxide nanomaterialsspecific surface areatransmission electron microscopyX-ray diffraction

Identifiers

PMID32932807
PMCPMC7558088

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.