ArticleViruses2020
What Should Health Departments Do with HIV Sequence Data?
Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- More evidence is needed to improve molecular HIV surveillance for cluster detection and response.Communications medicine · 2025Article
- Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance.Bioethics · 2025Article
- Risks, concerns, and benefits of molecular HIV Epidemiology in Public Health Practice: A qualitative exploration of perspectives among affected and interested communities.Journal of public health research · 2025Article
- Strategies and Opportunities to Improve Community Health through Advanced Molecular Detection and Genomic Surveillance of Infectious Diseases.Emerging infectious diseases · 2025Article
- User experience with HIV molecular epidemiology in research, surveillance, and cluster detection and response: a needs assessment.Current medical research and opinion · 2024Article
- Prospective Evaluation of Routine Statewide Integration of Molecular Epidemiology and Contact Tracing to Disrupt Human Immunodeficiency Virus Transmission.Open forum infectious diseases · 2024Article
- DeepDynaForecast: Phylogenetic-informed graph deep learning for epidemic transmission dynamic prediction.PLoS computational biology · 2024Article
- Public health use of HIV phylogenetic data in sub-Saharan Africa: ethical issues.BMJ global health · 2023Review
- Combining biomarker and virus phylogenetic models improves HIV-1 epidemiological source identification.PLoS computational biology · 2022Article
- Article
- Methods Combining Genomic and Epidemiological Data in the Reconstruction of Transmission Trees: A Systematic Review.Pathogens (Basel, Switzerland) · 2022Review
- Phylogenetic and Drug-Resistance Analysis of HIV-1 Sequences From an Extensive Paediatric HIV-1 Outbreak in Larkana, Pakistan.Frontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Many countries and US states have mandatory statues that require reporting of HIV clinical data including genetic sequencing results to the public health departments. Because genetic sequencing is a part of routine care for HIV infected persons; health departments have extensive sequence collections spanning years and even decades of the HIV epidemic. How should these data be used (or not) in public health practice? This is a complex; multi-faceted question that weighs personal risks against public health benefit. The answer is neither straightforward nor universal. However; to make that judgement-of how genetic sequence data should be used in describing and combating the HIV epidemic-we need a clear image of what a phylogenetically enhanced HIV surveillance system can do and what benefit it might provide. In this paper, we present a positive case for how up-to-date analysis of HIV sequence databases managed by health departments can provide unique and actionable information of how HIV is spreading in local communities. We discuss this question broadly, with examples from the US, as it is globally relevant for all health authorities that collect HIV genetic data.
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