Evidence map›Paper›PMID 32932604›Full record

ArticleJournal of clinical medicine2020

Effect of a Combination of Myo-Inositol, Alpha-Lipoic Acid, and Folic Acid on Oocyte Morphology and Embryo Morphokinetics in non-PCOS Overweight/Obese Patients Undergoing IVF: A Pilot, Prospective, Randomized Study.

Stefano Canosa, Carlotta Paschero, Andrea Carosso, Sara Leoncini, Noemi Mercaldo, Gianluca Gennarelli, Chiara Benedetto, Alberto Revelli

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07685431 (Effects of Alpha-Lipoic Acid Supplementation on Oocyte Quality, Cumulus Cell Mitochondrial Function, and In Vitro Fertilization Outcomes in Infertile Women of Advanced Maternal Age), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07685431 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Alpha-Lipoic Acid Supplementation on Oocyte Quality, Cumulus Cell Mitochondrial Function, and In Vitro Fertilization Outcomes in Infertile Women of Advanced Maternal Age: A Prospective Cohort Study

TypeinterventionalSponsorKaohsiung Veterans General Hospital.Ran2026 to 2028Enrolled60ConditionsFemale Infertility Due to Diminished Ovarian ReserveArmsAlpha-Lipoic Acid (ALA)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stefano CanosaGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.ORCID 0000-0001-6402-6750
Carlotta PascheroGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.ORCID 0000-0002-2263-5651
Andrea CarossoGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.ORCID 0000-0002-7734-4499
Sara LeonciniGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.
Noemi MercaldoGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.ORCID 0000-0002-4786-6085
Gianluca GennarelliGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.
Chiara BenedettoGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.
Alberto RevelliGynecology and Obstetrics 1, Physiopathology of Reproduction and IVF Unit, S. Anna Hospital, Department of Surgical Sciences, University of Torino, Via Ventimiglia 3, 10126 Torino, Italy.ORCID 0000-0002-5797-3722
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein we aimed at assessing whether Myo-Inositol (MI), Alpha-Lipoic acid (ALA), and Folic acid (FA) could improve oocyte quality and embryo development in non-PCOS overweight/obese women undergoing IVF. Three hundred and twenty-four mature oocytes were obtained from non-PCOS overweight/obese patients, randomized to receive either MI, ALA, and FA (MI + ALA + FA group,

Indexed as

embryo morphokineticsIVFMyo-Inositolobesityoocyte qualityoverweight patientspolarized light microscopy

Identifiers

PMID32932604
PMCPMC7564928
OpenAlexW3085417727

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.