Evidence map›Paper›PMID 32932594›Full record

ArticleMolecules (Basel, Switzerland)2020

The Reactions of H

Aleksandra Witkiewicz-Kucharczyk, Wojciech Goch, Jacek Olędzki, Andrea Hartwig, Wojciech Bal

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. New Advances in Short Peptides: Looking Forward.Molecules (Basel, Switzerland) · 2022
    Article
  2. Advances in Research of Short Peptides.Molecules (Basel, Switzerland) · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Aleksandra Witkiewicz-KucharczykInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.
Wojciech GochFaculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02097 Warsaw, Poland.ORCID 0000-0001-7230-7173
Jacek OlędzkiInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.
Andrea HartwigInstitute of Applied Biosciences, Karlsruhe Institute of Technology, 76021 Karlsruhe, Germany.ORCID 0000-0003-3826-3319
Wojciech BalInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5a, 02-106 Warsaw, Poland.
Institute of Biochemistry and Biophysics, Polish Academy of Sciences · PLKarlsruhe Institute of Technology · DEMedical University of Warsaw · PL

Funding

Narodowe Centrum Nauki 2012/07/N/NZ1/03090
6 · The paper itself

Abstract

Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLMNHFDLPTCDNCRDADDKHK-amide (XPAzf) as a working model to study the reaction of its Zn(II) complex (ZnXPAzf) with hydrogen peroxide and S-nitrosoglutathione (GSNO), as oxidative and nitrosative stress agents, respectively. We also used the Cd(II) substituted XPAzf (CdXPAzf) to assess the situation of cadmium assault, which is accompanied by oxidative stress. Using electrospray mass spectrometry (ESI-MS), HPLC, and UV-vis and circular dichroism spectroscopies we demonstrated that even very low levels of H

Indexed as

Amino Acid MotifsCadmiumChromatography, High Pressure LiquidCircular DichroismDNA RepairHumansHydrogen PeroxideNitrosative StressOxidative StressOxygenS-NitrosoglutathioneSpectrometry, Mass, Electrospray IonizationSulfhydryl CompoundsXeroderma Pigmentosum Group A ProteinZinc FingersCadmiumHydrogen PeroxideOxygenS-NitrosoglutathioneSulfhydryl CompoundsXeroderma Pigmentosum Group A ProteinXPA protein, humancadmiumhydrogen peroxideoxidationS-nitrosoglutathionezinczinc fingers

Identifiers

PMID32932594
PMCPMC7570819
OpenAlexW3081078650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.