Evidence map›Paper›PMID 32932322›Full record

ArticleAnnals of surgery2020

Persistent Racial and Sex Disparities in Outcomes After Coronary Artery Bypass Surgery: A Retrospective Clinical Registry Review in the Drug-eluting Stent Era.

Zachary Obinna Enumah, Joseph K Canner, Diane Alejo, Daniel S Warren, Xun Zhou, Gayane Yenokyan, Thomas Matthew, Jennifer S Lawton, Robert S D Higgins

Abstract readComparative Study
In one paragraph

Article in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Coronary artery surgery outcome differences by sex.Indian journal of thoracic and cardiovascular surgery · 2026
    Review
  9. Review
  10. Observational
  11. Article
  12. Article
  13. Racial and socioeconomic disparities in postoperative outcomes following coronary artery bypass grafting: a national inpatient analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  14. Observational
  15. Article
  16. Observational
  17. Review
  18. Article
  19. Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zachary Obinna EnumahJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Joseph K CannerJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Diane AlejoJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Daniel S WarrenJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Xun ZhouJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Gayane YenokyanJohns Hopkins Bloomberg School of Public Health, Department of Biostatistics, Baltimore, MD.
Thomas MatthewJohns Hopkins Suburban Hospital, Department of Cardiac Surgery, Bethesda, MD.
Jennifer S LawtonJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.
Robert S D HigginsJohns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD.

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Training In Orthopaedic Team ScienceT32AR067708 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI JONES, LYNNE C., SHAFIQ, BABAR · 2015 to 2024
$2.0M
NCATS NIH HHS UL1 TR003098NIAMS NIH HHS T32 AR067708
6 · The paper itself

Abstract

objectiveThe purpose of this study was to assess the temporal trends in 30-day mortality by race group for patients undergoing coronary artery bypass grafting (CABG) between 2011 and 2018 and to investigate the effect of race and sex on postoperative outcomes after CABG. SUMMARY BACKGROUND DATA: Cardiovascular diseases remain a leading cause of death in the United States with studies demonstrating increased morbidity and mortality for black and female patients undergoing surgery. In the post drug-eluting stent era, studies of racial disparities CABG are outdated.

methodsWe performed a retrospective analysis of the Society for Thoracic Surgeons database for patients undergoing CABG between 2011 and 2018. Primary outcome was 30-day mortality. Secondary outcomes included postoperative length of stay, surgical site infection, sepsis, pneumonia, stroke, reoperation, reintervention, early extubation, and readmission.

resultsThe study population was comprised of 1,042,506 patients who underwent isolated CABG between 2011 and 2018. Among all races, Black patients had higher rates of preoperative comorbidities. Compared with White patients, Black patients had higher overall mortality (2.76% vs 2.19%, P < 0.001). On univariable regression, Black patients had higher rates of death, infection, pneumonia, and postoperative stroke compared to White patients. On multivariable regression, Black patients had higher odds of 30-day mortality compared to white patients [odds ratio (OR) = 1.11, 95% confidence interval (CI) 1.05-1.18]. Similarly, female patients had higher odds of death compared to males (OR = 1.26, 95% CI 1.21-1.30).

conclusionsIn the modern era, racial and sex disparities in mortality and postoperative morbidity after coronary bypass surgery persist with Black patients and female patients consistently experiencing worse outcomes than White male patients. Although there may be unknown or underappreciated biological mechanisms at play, future research should focus on socioeconomic, cultural, and multilevel factors.

Indexed as

Coronary Artery BypassHealth Status DisparitiesAdultAgedAged, 80 and overBlack or African AmericanCoronary Artery DiseaseDrug-Eluting StentsFemaleHumansMaleMiddle AgedPostoperative ComplicationsRegistriesRetrospective StudiesSex Distribution

Identifiers

PMID32932322
PMCPMC8491278

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.