Evidence map›Paper›PMID 32931579›Full record

ArticleBioinformatics (Oxford, England)2021

COGENT: evaluating the consistency of gene co-expression networks.

Lyuba V Bozhilova, Javier Pardo-Diaz, Gesine Reinert, Charlotte M Deane

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lyuba V BozhilovaDepartment of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0000-0003-2784-2040
Javier Pardo-DiazDepartment of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0000-0001-9262-0482
Gesine ReinertDepartment of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.
Charlotte M DeaneDepartment of Statistics, University of Oxford, Oxford OX1 3LB, United Kingdom.ORCID 0000-0003-1388-2252

Funding

Biotechnology and Biological Sciences Research Council BB/T001801/1COST CA15109EPSRC EP/L016044/1e-Therapeutics plc
6 · The paper itself

Abstract

summaryGene co-expression networks can be constructed in multiple different ways, both in the use of different measures of co-expression, and in the thresholds applied to the calculated co-expression values, from any given dataset. It is often not clear which co-expression network construction method should be preferred. COGENT provides a set of tools designed to aid the choice of network construction method without the need for any external validation data. AVAILABILITY AND IMPLEMENTATION: https://github.com/lbozhilova/COGENT. SUPPLEMENTARY INFORMATION: Supplementary information is available at Bioinformatics online.

Indexed as

Gene Regulatory NetworksSoftwareDiagnostic Tests, RoutineGene Expression

Identifiers

PMID32931579
PMCPMC8317122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.