Evidence map›Paper›PMID 32931524›Full record

ArticlePloS one2020

Performance of an extended triage questionnaire to detect suspected cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in obstetric patients: Experience from two large teaching hospitals in Lombardy, Northern Italy.

Sara Ornaghi, Clelia Callegari, Roberta Milazzo, Laura La Milia, Federica Brunetti, Chiara Lubrano, Chiara Tasca, Stefania Livio, Valeria Maria Savasi, Irene Cetin and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Indirect impact of SARS-CoV-2 pandemic on pregnancy and childbirth outcomes: A nine-month long experience from a university center in Lombardy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sara OrnaghiDepartment of Obstetrics and Gynecology, Division of Obstetrics, MBBM foundation at San Gerardo Hospital, Monza, Italy.ORCID 0000-0001-6898-7217
Clelia CallegariDepartment of Obstetrics and Gynecology, Division of Obstetrics, MBBM foundation at San Gerardo Hospital, Monza, Italy.
Roberta MilazzoDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Laura La MiliaDepartment of Obstetrics and Gynecology, Division of Obstetrics, MBBM foundation at San Gerardo Hospital, Monza, Italy.
Federica BrunettiDepartment of Obstetrics and Gynecology, Division of Obstetrics, MBBM foundation at San Gerardo Hospital, Monza, Italy.
Chiara LubranoDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Chiara TascaDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Stefania LivioDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Valeria Maria SavasiDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Irene CetinDepartment of Clinical and Biological Sciences, University of Milan, Milan, Italy.
Patrizia VerganiDepartment of Obstetrics and Gynecology, Division of Obstetrics, MBBM foundation at San Gerardo Hospital, Monza, Italy.
University of Milan · ITAzienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives1. To assess the performance of an extended questionnaire in identifying cases of SARS-CoV-2 infection among obstetric patients. 2. To evaluate the rate of infection among healthcare workers involved in women's care. STUDY

designA prospective cohort study of obstetric patients admitted to MBBM Foundation and Buzzi Hospital (Lombardy, Northern Italy) from March 16th to May 22nd, 2020. Women were screened on admission by a questionnaire investigating major and minor symptoms of infection and high-risk contacts in the last 14 days. SARS-CoV-2 assessment was performed by RT-PCR on nasopharyngeal swabs. Till April 7th, a targeted SARS-CoV-2 testing triggered by a positive questionnaire was used; from April 8th, a universal testing approach was implemented.

resultsThere were 1,177 women screened by the questionnaire, which yielded a positive result in 130 (11.0%) cases. SARS-CoV-2 RT-PCR was performed in 865 (73.5%) patients, identifying 51 (5.9%) infections. During the first period, there were 29 infected mothers, 4 (13.8%) of whom had a negative questionnaire. After universal testing implementation, there were 22 (3%, 95% CI 1.94% - 4.04%) infected mothers, 13 (59.1%) of whom had a negative questionnaire; rate of infection among asymptomatic women was 1.9%. Six of the 17 SARS-CoV-2-positive women with a negative questionnaire reported symptoms more than 14 but within 30 days before admission. Isolated olfactory or taste disorders were identified in 15.7% of infected patients. Rate of infection among healthcare workers was 5.8%.

conclusionsAn exhaustive triage questionnaire can effectively discriminate women at low risk of SARS-CoV-2 infection in the context of a targeted and a universal viral testing approach. In 15.7% of infected women, correct classification as a suspected case of infection was due to investigation of olfactory and taste disorders. Extension of the assessed time-frame to 30 days may be worth considering to increase the questionnaire's performance.

Indexed as

AdultAsymptomatic DiseasesBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHealth PersonnelHospitals, TeachingHumansItalyNasopharynxPandemicsPneumonia, ViralProspective StudiesReverse Transcriptase Polymerase Chain ReactionRNA, ViralRNA, Viral

Identifiers

PMID32931524
PMCPMC7491723
OpenAlexW3086365716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.