Evidence map›Paper›PMID 32931413›Full record

Trial reportBlood transfusion = Trasfusione del sangue2020

Bacterial contamination of blood products for transfusion in the Democratic Republic of the Congo: temperature monitoring, qualitative and semi-quantitative culture.

Anne-Sophie Heroes, Natacha Ndalingosu, Jocelyne Kalema, Aimée Luyindula, Dorothée Kashitu, Catherine Akele, Jeff Kabinda, Katrien Lagrou, Philippe Vandekerckhove, Jan Jacobs and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Blood transfusion = Trasfusione del sangue, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Use of flow cytometry method to detect contaminations of platelet suspensions.World journal of microbiology & biotechnology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne-Sophie HeroesInstitute of Tropical Medicine, Department of Clinical Sciences, Antwerp, Belgium.
Natacha NdalingosuCentre National de Transfusion Sanguine, Hemovigilance Department, Kinshasa, Democratic Republic of the Congo.
Jocelyne KalemaInstitut National de Recherche Biomédicale, Department of Microbiology, Kinshasa, Democratic Republic of the Congo.
Aimée LuyindulaHôpital Saint-Luc, Blood bank, Kisantu, Democratic Republic of the Congo.
Dorothée KashituHôpital Provincial Général de Référence, Blood Bank, Kinshasa, Democratic Republic of the Congo.
Catherine AkeleHôpital Pédiatrique Kalembe Lembe, Head Office, Kinshasa, Democratic Republic of the Congo.
Jeff KabindaUniversité Pédagogique Nationale, Department of Health Science, Kinshasa, Democratic Republic of the Congo.
Katrien LagrouUniversity Hospitals Leuven, Department of Laboratory Medicine and National Reference Centre for Mycosis, Leuven, Belgium.
Philippe VandekerckhoveBelgian Red Cross-Flanders, Blood service, Mechelen, Belgium.
Jan JacobsInstitute of Tropical Medicine, Department of Clinical Sciences, Antwerp, Belgium.
Octavie LunguyaInstitut National de Recherche Biomédicale, Department of Microbiology, Kinshasa, Democratic Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial contamination of blood for transfusion is rarely investigated in low-income countries. We determined the contamination rate of blood products in the Democratic Republic of the Congo. MATERIAL AND

methodsIn this prospective observational study, blood products in one rural and two urban hospitals (paediatric and general) contained a satellite sampling bag by which blood was sampled for culture in a blood culture bottle (4 mL) and on an agar-coated slide to estimate colony forming units (CFU/mL). Bacteria were identified with biochemical tests and MALDI-TOF (Bruker). Exposure time >10 °C was assessed on a subset of blood products.

resultsIn total, 1.4% (41 of 2,959) of blood products were contaminated with 48 bacterial isolates. Skin (e.g., Staphylococcus spp.) and environmental (e.g., Bacillus spp.) bacteria predominated (97.8% of 45 isolates identified). Bacterial counts were ≤10 DISCUSSION: A bacterial contamination rate of 1.4% of whole blood and red cells is similar to results from high-income countries. Implementation of feasible risk-mitigation measures is needed.

Indexed as

Blood Component TransfusionBlood DonorsBlood SafetyTemperatureAdultBacillusDemocratic Republic of the CongoFemaleHumansMaleStaphylococcusTime Factors

Identifiers

PMID32931413
PMCPMC7592166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.