Evidence map›Paper›PMID 32931337›Full record

ArticleCirculation. Arrhythmia and electrophysiology2020

Genetic Loss of

Louise Reilly, Francisco J Alvarado, Di Lang, Sara Abozeid, Hannah Van Ert, Cordell Spellman, Jarrett Warden, Jonathan C Makielski, Alexey V Glukhov, Lee L Eckhardt

Open access · bronzeAbstract read
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Beta-Adrenergic Activation of the Inward Rectifier KInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Louise ReillyCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Francisco J AlvaradoCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Di LangCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Sara AbozeidCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Hannah Van ErtCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Cordell SpellmanCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Jarrett WardenCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Jonathan C MakielskiCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Alexey V GlukhovCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
Lee L EckhardtCellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison.
University of Wisconsin–Madison · US

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
RYANODINE RECEPTORS, Ca2+-TRIGGERED ARRHYTHMIAS AND HCMP01HL094291 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VALIDA, HECTOR · 2009 to 2013
$9.7M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Arrhythmia Mechanisms from Inherited and Acquired Caveolin3 Dysregulation of IK1R01HL128598 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ECKHARDT, LEE LOCHBAUM · 2015 to 2019
$1.9M
KCNJ2-Induced Arrhythmia Mechanisms in CPVT and Heart Failure.R01HL139738 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ECKHARDT, LEE LOCHBAUM · 2018 to 2021
$1.5M
NHLBI NIH HHS P01 HL094291NHLBI NIH HHS R01 HL128598NHLBI NIH HHS R01 HL139738NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444
6 · The paper itself

Abstract

backgroundArrhythmia syndromes associated with

methodsA cardiac-specific

resultsR67Q

conclusions

Indexed as

Action PotentialsHeart RateAdrenergic AgonistsAdultAnimalsCalcium SignalingDisease Models, AnimalEpinephrineFemaleG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHeterozygoteHumansIsolated Heart PreparationIsoproterenolMaleMice, 129 StrainAdrenergic AgonistsEpinephrineG Protein-Coupled Inwardly-Rectifying Potassium ChannelsIsoproterenolKCNJ3 protein, humanKcnj3 protein, mouseaction potentialheartpotassium channelssarcoplasmic reticulumtachycardia, ventricular

Identifiers

PMID32931337
PMCPMC7574954
OpenAlexW3047154471

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.