ArticleAIDS patient care and STDs2020
Exploring the Engagement of Racial and Ethnic Minorities in HIV Treatment and Vaccine Clinical Trials: A Scoping Review of Literature and Implications for Future Research.
Article in AIDS patient care and STDs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Barriers and facilitators for recruiting and retaining male participants into longitudinal health research: a systematic review.BMC medical research methodology · 2024Pooled it
- Trial
- Trial
- Characteristics of drug-involved black women under community supervision; implications for retention in HIV clinical trials and healthcare.Social work in health careTrial
- From Youth Advisory Boards to subject matter research consultants: transforming youth participation in research advising and practice.Research involvement and engagement · 2026Article
- Medical-Legal Partnerships as Structural Interventions: Integrating Implementation Science and Community-Engaged Research to Advance HIV Care.Journal of the International AIDS Society · 2026Article
- Racial disparities in ophthalmology clinical trials: barriers to participation and potential solutions.Eye (London, England) · 2026Review
- Mpox Vaccination and Willingness to Participate in Mpox Vaccine Research Among Sexual and Gender Minority Adults with and Without HIV in the United States.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Tailoring an auricular point acupressure self-management program for chronic pain: lessons learned from rural partners.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Insights from the development of an online toolkit to promote community engaged substance use research in the Southwest Borderlands Region.Research square · 2025Article
- Social Impacts of Multi-City HIV Research Participation Among Sexual and Gender Expansive Individuals in Kazakhstan.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Medical mistrust and vaccine-hesitant attitudes explain SARS-CoV-2 vaccination disparities in a mixed serostatus cohort.AIDS (London, England) · 2025Article
- The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research.Prevention science : the official journal of the Society for Prevention Research · 2024Article
- Oncologists' perceptions of tumor genomic profiling and barriers to communicating secondary hereditary risks to African American cancer patients.BMC cancer · 2024Article
- Determinants of an HIV Preventive Vaccine among a Highly Vulnerable Population: African American Men Who Have Sex with Men.Vaccines · 2024Article
- Evaluating enrollment and representation in COVID-19 and HIV vaccine clinical trials.Frontiers in public health · 2024Article
- A commentary on forging a path for CHANGE: culturally focused HIV training for the next generation in pursuit of equity.Critical public health · 2024Article
- A toolkit for capturing a representative and equitable sample in health research.Nature medicine · 2023Article
- 2022 consensus conference on diversity, equity, and inclusion: Developing an emergency medicine research agenda for addressing racism through health care research.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2023Article
- An Equity and Justice-Informed Ethical Framework to Guide Incidental Findings in Brain Imaging Research.Clinics and practice · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
HIV disproportionately impacts US racial and ethnic minorities but they participate in treatment and vaccine clinical trials at a lower rate than whites. To summarize barriers and facilitators to this participation we conducted a scoping review of the literature guided by the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Studies published from January 2007 and September 2019 were reviewed. Thirty-one articles were identified from an initial pool of 325 records using three coders. All records were then assessed for barriers and facilitators and summarized. Results indicate that while racial and ethnic minority participation in these trials has increased over the past 10 years, rates still do not proportionately reflect their burden of HIV infection. While many of the barriers mirror those found in other disease clinical trials (e.g., cancer), HIV stigma is a unique and important barrier to participating in HIV clinical trials. Recommendations to improve recruitment and retention of racial and ethnic minorities include training health care providers on the importance of recruiting diverse participants, creating interdisciplinary research teams that better represent who is being recruited, and providing culturally competent trial designs. Despite the knowledge of how to better recruit racial and ethnic minorities, few interventions have been documented using these strategies. Based on the findings of this review, we recommend that future clinical trials engage community stakeholders in all stages of the research process through community-based participatory research approaches and promote culturally and linguistically appropriate recruitment and retention strategies for marginalized populations overly impacted by HIV.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.