Evidence map›Paper›PMID 32931157›Full record

ArticleJournal of cellular and molecular medicine2020

Periosteum progenitors could stimulate bone regeneration in aged murine bone defect model.

Han Xiao, Linfeng Wang, Tao Zhang, Can Chen, Huabin Chen, Shengcan Li, Jianzhong Hu, Hongbin Lu

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. PRRX1 upregulates PD-L1 in human mesenchymal stem cells.In vitro cellular & developmental biology. Animal · 2024
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  5. Fractures in elderly mice demonstrate delayed ossification of the soft callus: a cellular and radiographic study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Article
  6. TheJBMR plus · 2023
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Han XiaoDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0003-4283-4559
Linfeng WangDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Tao ZhangDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Can ChenDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Huabin ChenDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Shengcan LiDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jianzhong HuKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, China.
Hongbin LuDepartment of Sports Medicine, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periosteal stem cells are critical for bone regeneration, while the numbers will decrease with age. This study focused on whether Prx1

Indexed as

Bone RegenerationAgingAnimalsBiomechanical PhenomenaBone and BonesCell CountCell DifferentiationCell ProliferationCell SeparationDisease Models, AnimalFracture HealingHomeodomain ProteinsMesenchymal Stem CellsMice, Inbred C57BLOsteogenesisPeriosteumHomeodomain ProteinsPrrx1 protein, mouseaged micebone defectbone regenerationperiosteum derived cellsPrx1+ MSCPrx1− MSC

Identifiers

PMID32931157
PMCPMC7579685
OpenAlexW3084540402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.