ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Comparing EQ-5D-3L and EQ-5D-5L performance in common cancers: suggestions for instrument choosing.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of life in patients with non-small cell lung cancer treated with PD-1/PD-L1 inhibitors: a systematic review and meta-analysis.World journal of surgical oncology · 2022Pooled it
- A randomised trial comparing 6-monthly adjuvant zoledronate with a single one-time dose in patients with early breast cancer.Breast cancer research and treatment · 2024Trial
- Impact of lung cancer diagnosis on patient lifestyle and physical activity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Observational
- Caregivers' proxy assessments of health-related quality of life in patients with hematologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Health related quality of life of patients with breast cancer in Malaysia: evidence from EQ-5D-5L and EORTC QLQ-C30.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Validation of the Spanish Version of the Wound-QoL-14 Wound-Specific Health-Related Quality of Life Questionnaire.International wound journal · 2026Article
- Is EQ-5D-5L better than EQ-5D-3L? A comparison of descriptive systems and utility scores in patients with kidney chronic disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Dynamic screening for anxiety and depression in patients undergoing primary surgery for gastrointestinal cancer.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Development of mapping algorithms for gastric cancer: translating EORTC QLQ-C30 and QLQ-STO22 to EQ-5D-5L health utilities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Associations between financial toxicity, health-related quality of life, and well-being in Indonesian patients with breast cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Cost-effectiveness of low-dose CT screening for non-smokers with a first-degree relative history of lung cancer.BMC public health · 2025Article
- Mapping the ADDQoL to the EQ-5D-5L and SF-6Dv2 among Chinese patients with type 2 diabetes mellitus.Health and quality of life outcomes · 2025Article
- Assessment of Health-Related Quality of Life in Thai Endometrial Cancer Patients: A Comparative Analysis Using EQ5D Utility Scores Across States.Cancer reports (Hoboken, N.J.) · 2025Article
- Cross-cultural adaptation and validation of the Chinese version of the 25-question Geriatric Locomotive Function Scale in patients undergoing total knee arthroplasty.Frontiers in medicine · 2025Article
- Altered patterns in the prefrontal cortex and limbic system in female patients with neuropathic pain secondary to recurrent median nerve entrapment post carpal tunnel release.Brain communications · 2025Article
- The generic version of China Health Related Outcomes Measures (CHROME-G): psychometric testing and comparative performance with the EQ-5D-5L and SF-6Dv2 among the Chinese general population.BMC public health · 2024Article
- Indolent growth of low‑grade myofibroblastic sarcoma of the knee with the resemblance of a benign lesion: A case report.Oncology letters · 2024Article
- Development of algorithms to estimate the EQ-5D-5L from the FACT-L in patients with lung cancer: a mapping study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Risk-based lung cancer screening in heavy smokers: a benefit-harm and cost-effectiveness modeling study.BMC medicine · 2024Article
- Effect of dexamethasone pretreatment using deep learning on the surgical effect of patients with gastrointestinal tumors.PloS one · 2024Article
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Authors and funding
16 authors.
Funding
Abstract
purposeTo compare the performance of three-level EuroQol five-dimensions (EQ-5D-3L) and five-level EuroQol five-dimensions (EQ-5D-5L) among common cancer patients in urban China.
methodsA hospital-based cross-sectional survey was conducted in three provinces from 2016 to 2018 in urban China. Patients with breast cancer, colorectal cancer, or lung cancer were recruited to complete the EQ-5D-3L and EQ-5D-5L questionnaires. Response distribution, discriminatory power (indicator: Shannon index [H'] and Shannon evenness index [J']), ceiling effect (the proportion of full health state), convergent validity, and health-related quality of life (HRQoL) were compared between the two instruments.
resultsA total of 1802 cancer patients (breast cancer: 601, colorectal cancer: 601, lung cancer: 600) were included, with the mean age of 55.6 years. The average inconsistency rate was 4.4%. Compared with EQ-5D-3L (average: H' = 1.100, J' = 0.696), an improved discriminatory power was observed in EQ-5D-5L (H' = 1.473, J' = 0.932), especially contributing to anxiety/depression dimensions. The ceiling effect was diminished in EQ-5D-5L (26.5%) in comparison with EQ-5D-3L (34.5%) (p < 0.001), mainly reflected in the pain/discomfort and anxiety/depression dimensions. The overall utility score was 0.790 (95% CI 0.778-0.801) for EQ-5D-3L and 0.803 (0.790-0.816) for EQ-5D-5L (p < 0.001). A similar pattern was also observed in the detailed cancer-specific analysis.
conclusionsWith greater discriminatory power, convergent validity and lower ceiling, EQ-5D-5L may be preferable to EQ-5D-3L for the assessment of HRQoL among cancer patients. However, higher utility scores derived form EQ-5D-5L may also lead to lower QALY gains than those of 3L potentially in cost-utility studies and underestimation in the burden of disease.
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