Evidence map›Paper›PMID 32930511›Full record

ReviewPediatric pulmonology2021

Obesity-related asthma in children: A role for vitamin D.

Brian P O'Sullivan, Laura James, Joseph M Majure, Scott Bickel, Ly-Thao Phan, Monica Serrano Gonzalez, Heather Staples, Jade Tam-Williams, Jason Lang, Jessica Snowden and 1 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03686150 (Vitamin D Oral Replacement in Asthma), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03686150 nacompletednot on this map

Vitamin D Oral Replacement in Asthma

TypeinterventionalSponsorIDeA States Pediatric Clinical Trials NetworkRan2019 to 2021Enrolled112ConditionsAsthma, Vitamin D Deficiency, Pediatric ObesityArmsVitamin D3 oral regimen
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. [Observation and analysis of Vitamin D levels in 147 children undergoing adenoidectomy and/or tonsillectomy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  6. Article
  7. Review
  8. Management of the pediatric patient with asthma and obesity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  18. The Sun also rises.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Brian P O'SullivanDepartment of Pediatrics, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire, USA.
Laura JamesDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Joseph M MajureDepartment of Pediatrics, University of Mississippi, Oxford, Mississippi, USA.
Scott BickelDepartment of Pediatrics, University of Louisville, Louisville, Kentucky, USA.
Ly-Thao PhanDepartment of Pediatrics, Nemours Children's Health System, Wilmington, Delaware, USA.
Monica Serrano GonzalezDepartment of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-0346-8840
Heather StaplesDepartment of Pediatrics, University of South Carolina, Columbia, South Carolina, USA.
Jade Tam-WilliamsDepartment of Pediatrics, University of Missouri-Kansas School of Medicine and Children's Mercy Hospital, Kansas City, Missouri, USA.
Jason LangDuke Clinical Research Institute and Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0001-9115-5312
Jessica SnowdenDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-0715-151X
IDeA States Pediatric Clinical Trials Network
University of Arkansas for Medical Sciences · USBrown University · USChildren's Mercy Hospital · USDartmouth College · USDuke University · USNemours Children's Health System · USUniversity of Louisville · USUniversity of Mississippi · USUniversity of South Carolina · US

Funding

Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials NetworkU24OD024957 · OD · UNIV OF ARKANSAS FOR MED SCIS · PI COURTNEY, SHERRY, OUNPRASEUTH, SONGTHIP T. · 2016 to 2024
$80.8M
IMproving Pediatric Access to Clinical Trials in Vermont (IMPACT VT)UG1OD024955 · OD · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Kelly Jean Cowan, Leslie W Young · 2016 to 2026
$4.8M
MS-ISPCTN (Cycle 3)UG1OD024942 · OD · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joseph Marc Majure · 2016 to 2026
$4.7M
Sunflower Pediatric Clinical Trials (SPeCTr 3.0)UG1OD024943 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Ann M Davis, BRIDGETTE L. JONES · 2016 to 2026
$4.7M
Rhode Island Child Clinical Trials CollaborativeUG1OD024951 · OD · RHODE ISLAND HOSPITAL · PI THOMAS H CHUN, PHYLLIS A. DENNERY · 2016 to 2026
$4.7M
UNM Pediatric Clinical Trial Sites in IDeA State Pediatric Clinical Trial NetworkUG1OD024947 · OD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Jessie R. Maxwell, Hengameh H Raissy · 2016 to 2026
$4.6M
ISPCTN Pediatric Clinical Trials UnitUG1OD024946 · OD · DARTMOUTH-HITCHCOCK CLINIC · PI Tyler Hartman, Paul E. Palumbo · 2016 to 2026
$4.6M
The DE Nemours/duPont Hospital for Children IDeA States Pediatric Clinical Trials Network SiteUG1OD024958 · OD · NEMOURS CHILDREN'S HOSPITAL, DELAWARE · PI Robert E Akins, Thao-Ly Tam Phan-Vo · 2016 to 2026
$4.5M
Montana Pediatric Clinical Trials SiteUG1OD024952 · OD · UNIVERSITY OF MONTANA · PI Emily Hall, Erin O'Brien Semmens · 2016 to 2026
$4.4M
The Nebraska Pediatric Clinic Trials UnitUG1OD024953 · OD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Bradford A Brabec, Ellen Kerns · 2016 to 2026
$4.4M
Trials and ReseArch Network FOR even More- South Carolina (TRANSFORM-3)UG1OD024956 · OD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ANDREW M ATZ, Lisa Knight · 2016 to 2026
$4.3M
The Kentucky Pediatric Clinical Trials Rural/Urban PartnershipUG1OD024954 · OD · UNIVERSITY OF LOUISVILLE · PI Lori Ann Devlin-Phinney, Sara E Watson · 2016 to 2026
$4.3M
NICHD NIH HHS K23 HD083439NICHD NIH HHS UG1 HD090849NIH HHS U24 OD024957NIH HHS UG1 OD024942NIH HHS UG1 OD024943NIH HHS UG1 OD024944NIH HHS UG1 OD024945NIH HHS UG1 OD024946NIH HHS UG1 OD024947NIH HHS UG1 OD024948NIH HHS UG1 OD024949NIH HHS UG1 OD024950NIH HHS UG1 OD024951NIH HHS UG1 OD024952NIH HHS UG1 OD024953NIH HHS UG1 OD024954NIH HHS UG1 OD024955NIH HHS UG1 OD024956NIH HHS UG1 OD024958NIH HHS UG1 OD024959
6 · The paper itself

Abstract

Excess adipose tissue predisposes to an enhanced inflammatory state and can contribute to the pathogenesis and severity of asthma. Vitamin D has anti-inflammatory properties and low-serum levels are seen in children with asthma and in children with obesity. Here we review the intersection of asthma, obesity, and hypovitaminosis D in children. Supplementation with vitamin D has been proposed as a simple, safe, and inexpensive adjunctive therapy in a number of disease states. However, little research has examined the pharmacokinetics of vitamin D and its therapeutic potential in children who suffer from obesity-related asthma.

Indexed as

AsthmaDietary SupplementsObesityVitamin DVitaminsChildHumansInflammationVitamin D DeficiencyVitamin DVitaminsasthmachildreninflammationobesitypediatricvitamin D

Identifiers

PMID32930511
PMCPMC8341445
OpenAlexW3084677644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.