Evidence map›Paper›PMID 32930507›Full record

ArticleJournal of midwifery & women's health2021

The Role of Oxytocin in Primary Cesarean Birth Among Low-Risk Women.

Rebecca R S Clark, Nicole Warren, Kenneth M Shermock, Nancy Perrin, Eileen Lake, Phyllis W Sharps

Open access · greenAbstract read
In one paragraph

Article in Journal of midwifery & women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Carbetocin Controls Intraoperative Blood Loss and Thickness of Myometrium in Scar Uterus Cases.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rebecca R S ClarkCenter for Health Outcomes and Policy Research, Department of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania.ORCID 0000-0001-7284-3523
Nicole WarrenDepartment of Community and Public Health, Johns Hopkins University School of Nursing, Baltimore, Maryland.
Kenneth M ShermockCenter for Medication Safety and Quality, Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland.
Nancy PerrinBiostatistics and Methods Core, Johns Hopkins University School of Nursing, Baltimore, Maryland.
Eileen LakeCenter for Health Outcomes and Policy Research, Department of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania.
Phyllis W SharpsDepartment of Community and Public Health, Johns Hopkins University School of Nursing, Baltimore, Maryland.
Johns Hopkins University · USUniversity of Pennsylvania · US

Funding

ADVANCED TRAINING IN NURSING OUTCOMES RESEARCHT32NR007104 · NINR · UNIVERSITY OF PENNSYLVANIA · PI JACQUELINE MARGO BROOKS CARTHON, EILEEN T LAKE · 1999 to 2026
$11.6M
NINR NIH HHS Advanced Training in Nursing Outcomes Research T32NINR NIH HHS T32 NR007104Robert Wood Johnson Foundation Future of Nursing Scholars Award
6 · The paper itself

Abstract

introductionTo examine whether there is a threshold of oxytocin exposure at which the risk for primary cesarean increases among women who are nulliparous with a term, singleton, vertex fetus (NTSV) and how oxytocin interacts with other risk factors to contribute to this outcome.

methodsThis was a secondary analysis of the Consortium on Safe Labor data set that used a retrospective cohort study design. Women who met the criteria for NTSV who were not admitted for a prelabor cesarean and for whom oxytocin data were available, were included in the sample. Robust logistic regression was used to examine the association of oxytocin exposure with primary cesarean birth, while controlling for demographic and clinical risk factors and clustering by provider.

resultsThe sample comprised 17,331 women who were exposed to oxytocin during labor. The women were predominantly white non-Hispanic (59.2%) with an average (SD) gestational age of 39.4 (1.1) weeks and an 18.5% primary cesarean rate. Exposure to greater than 11,400-milliunits (mU) of oxytocin resulted in 1.6 times increased odds of primary cesarean birth compared with less than 11,400 mU (95% CI 1.01-2.6). DISCUSSION: Exposure to greater than 11,400 mU of oxytocin in labor was associated with an increased odds of primary cesarean birth in NTSV women.

Indexed as

AdolescentAdultCesarean SectionFemaleHumansLabor, InducedLabor, ObstetricLogistic ModelsObstetric Labor ComplicationsObstetricsOxytocicsOxytocinParityPregnancyPregnancy OutcomeRetrospective StudiesOxytocicsOxytocinbirthcesarean sectioninduced laborobstetric laboroxytocin

Identifiers

PMID32930507
PMCPMC7897216
OpenAlexW3087754997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.