ArticleJournal of biomedical materials research. Part B, Applied biomaterials2021
In vitro methodology for medical device material thrombogenicity assessments: A use condition and bioanalytical proof-of-concept approach.
Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Thrombogenicity of stent graft materials as a potential contributing factor to limb graft occlusions.JVS-vascular science · 2026Article
- Evaluation of Ultrasonic Spray Method for Application of Sirolimus-Eluting Coating on Bioresorbable Vascular Scaffolds.International journal of molecular sciences · 2025Article
- Alternative Anticoagulant Strategy to Improve the Test Sensitivity of ASTM F2888-19 Standard for Platelet and Leukocyte Count Assay.Journal of biomedical materials research. Part B, Applied biomaterials · 2024Article
- Molecular Biomarkers for In Vitro Thrombogenicity Assessment of Medical Device Materials.Journal of biomedical materials research. Part B, Applied biomaterials · 2024Article
- Efficacy of closed cell self expandable metallic stent for peripheral arterial disease in the porcine iliac artery.Scientific reports · 2023Article
- Efficacy of thermoplastic polyurethane and gelatin blended nanofibers covered stent graft in the porcine iliac artery.Scientific reports · 2022Article
- (More than) doubling down: Effective fibrinolysis at a reduced rt-PA dose for catheter-directed thrombolysis combined with histotripsy.PloS one · 2022Article
- In vitro methodology for medical device material thrombogenicity assessments: A use condition and bioanalytical proof-of-concept approach.Journal of biomedical materials research. Part B, Applied biomaterials · 2021Article
- Effect of First Long-Term Training on Whole Blood Count and Blood Clotting Parameters in Thoroughbreds.Animals : an open access journal from MDPI · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Device manufacturers and regulatory agencies currently utilize expensive and often inconclusive in vivo vascular implant models to assess implant material thrombogenicity. We report an in vitro thrombogenicity assessment methodology where test materials (polyethylene, Elasthane™ 80A polyurethane, Pebax®), alongside positive (borosilicate glass) and negative (no material) controls, were exposed to fresh human blood, with attention to common blood-contact use conditions and the variables: material (M), material surface modification (SM) with heparin, model (Mo), time (T), blood donor (D), exposure ratio (ER; cm
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