Evidence map›Paper›PMID 32929855›Full record

Trial reportJournal of cosmetic dermatology2021

Early and maintained application of the secretion of Cryptomphalus aspersa (SCA) 40% improves cutaneous healing after ablative fractional laser in skin aging.

Pablo Fernandez-Gonzalez, Maria Vitale, M Teresa Truchuelo

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cosmetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Pablo Fernandez-GonzalezHospital Central de la Defensa, Madrid, Spain.
Maria VitaleMedical Department of Cantabria labs at Madrid, Madrid, Spain.
M Teresa TruchueloVithas Nuestra Señora de América Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0002-9691-0476
Hospital Central de la Defensa Gómez Ulla · ESHospital Nuestra Señora de Alarcos · ESUniversidad de Cantabria · ES

Funding

Cantabrialabs
6 · The paper itself

Abstract

backgroundAblative fractional laser generates a regulated skin damage, which secondarily improves skin aging.

aimsThe main objective of the present study was to figure out if the adverse effects induced by laser and the skin recovery could improve with the application of a cosmetic product based on the secretion of Cryptomphalus aspersa (SCA). PATIENTS/

methodsA prospective double-blind controlled study with vehicle in 10 patients with skin aging. The patients received one session of fractional ablative CO

resultsSignificant greater decrease in the density of microcolumns produced by laser was detected on the active-treated side, indicating greater and faster postprocedure recovery compared to the vehicle-treated side. In addition, side effects were reduced and some antiaging effects were more apparent on the side treated with SCA 40%.

conclusionSCA 40% applied immediately after ablative laser, and during the next days, it can accelerate laser-induced damage regeneration. In addition, SCA improves the cosmetic outcome after laser application.

Indexed as

Lasers, GasLaser TherapySkin AgingAdministration, CutaneousFemaleHumansProspective StudiesSkinablative laserCO2 laserlaser recoveryskin agingtreatment

Identifiers

PMID32929855
PMCPMC8048427
OpenAlexW3087595524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.