Evidence map›Paper›PMID 32929689›Full record

ArticleInfectious diseases and therapy2020

Seroprevalence of Hepatitis B Virus Infection, Mother-To-Child Transmission, and Associated Risk Factors Among Delivering Mothers in Tigray Region, Northern Ethiopia: a Cross-Sectional Study.

Kbrom Gemechu Kiros, Mekonnen Haftom Goyteom, Yohannes Ashebir Tesfamichael, Haftea Hagos Mekonen, Tsegu Hailu Gebru, Tesfay Gebreslassie Gebrehiwot, Yared Hailesilassie Teka, Woldu Aberhe Abrha, Degena Bahrey Tadesse

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kbrom Gemechu KirosDepartment of Nursing, Adigrat University, Adigrat, Ethiopia. kbrom.gemechu@adu.edu.et.
Mekonnen Haftom GoyteomDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Yohannes Ashebir TesfamichaelDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Haftea Hagos MekonenDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Tsegu Hailu GebruDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Tesfay Gebreslassie GebrehiwotDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Yared Hailesilassie TekaDepartment of Nursing, Adigrat University, Adigrat, Ethiopia.
Woldu Aberhe AbrhaSchool of Nursing, College of Health Sciences and Comprehensive Specialized Hospital, Aksum University, Tigray, Ethiopia.
Degena Bahrey TadesseSchool of Nursing, College of Health Sciences and Comprehensive Specialized Hospital, Aksum University, Tigray, Ethiopia.
Adigrat University · ETAksum University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHigh prevalence of hepatitis B virus (HBV) infection among pregnant women is the primary source of infection for their children and the general population. Mother-to-child transmission (MTCT) is the primary mode of transmission in endemic areas like Ethiopia. The aim of this study was to determine the prevalence of HBV infection, rate of MTCT, and associated risk factors among delivering mothers.

methodsThis health facility-based cross-sectional study was conducted in four public hospitals of the Eastern zone of Tigray among 473 delivering mothers. Structured questionnaires and laboratory results were used to collect the data. The data were checked for completeness and entered into EpiData manager version 4.6.0.0. Then the data were exported to Statistical Package for Social Sciences (SPSS) version 23. The odds ratio, along with a 95% confidence interval, was estimated to identify predictors of HBV infection using multivariable logistic regression analysis. Significant association was considered at p < 0.05.

resultsA total of 473 mothers were enrolled, and the response rate was 100%. The prevalence of HBV infection among the mothers and the rate of MTCT of the infection were 11.6% and 30.9%, respectively. History of home delivery [adjusted odds ratio (AOR) = 4.5, 95% confidence interval (CI) (2, 10.6)], history of hospital admission [AOR = 5, 95% CI (2.2, 11.5)], working at health facility [AOR = 5.4, 95% CI (1.4, 20.7)], body tattoos [AOR = 5.8, 95% CI (2.4, 13.6)], sharing personal care materials [AOR = 3.8, 95% CI (1.4, 9.9)], insufficient knowledge [AOR = 5.6, 95% CI (1.6, 19)], and having human immunodeficiency virus (HIV) [AOR = 5.1, 95% CI (1, 26.2)] were significantly associated with HBV infection.

conclusionHBV infection among delivering women is becoming highly endemic, and the rate of MTCT was high. Therefore, administering hepatitis B vaccine to all neonates within 24 h of birth is mandatory to prevent MTCT of HBV infection and related complications. Furthermore, health education and dissemination of information about HBV for the pregnant mothers are needed to reduce HBV infection and vertical transmission in Ethiopia.

Indexed as

Associated factorsHepatitis B virusMother-to-child transmissionPregnant mother

Identifiers

PMID32929689
PMCPMC7680472
OpenAlexW3085957097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.