ArticleProtoplasma2021
MiR396 regulatory network and its expression during grain development in wheat.
Article in Protoplasma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The multifaceted regulatory network of microRNA396: Orchestrating plant plasticity through coordinating development and various stresses.Journal of integrative plant biology · 2026Review
- Integrative multi-omics analysis uncovers the regulatory network of wheat grain development during grain filling.BMC plant biology · 2026Article
- Identification and characterization of the miR396f-GRF10 module in phase transition of Lilium.Planta · 2025Article
- Non-coding RNAs and their role in plants: prospective omics-tools for improving growth, development and stress tolerance in field crops.Molecular biology reports · 2025Review
- Identification and Analysis of lncRNA and circRNA Related to Wheat Grain Development.International journal of molecular sciences · 2024Article
- Article
- BpGRP1 acts downstream of BpmiR396c/BpGRF3 to confer salt tolerance in Betula platyphylla.Plant biotechnology journal · 2024Article
- Endoplasmic reticulum stress-responsive microRNAs are involved in the regulation of abiotic stresses in wheat.Plant cell reports · 2023Article
- Screening of Reference miRNA of Different Early- and Late-Flowering Tree Peony Varieties.Plants (Basel, Switzerland) · 2023Article
- Article
- Multiple Functions of MiRNAs inLife (Basel, Switzerland) · 2022Review
- Identification of long non-coding RNAs and microRNAs involved in anther development in the tropical Camellia oleifera.BMC genomics · 2022Article
- Integrated mRNA and Small RNA Sequencing Reveals a microRNA Regulatory Network Associated with Starch Biosynthesis in Lotus (International journal of molecular sciences · 2022Article
- N6-Methyladenosine dynamic changes and differential methylation in wheat grain development.Planta · 2022Article
- Identification and profiling of conserved microRNAs in different developmental stages of crown imperial (Fritillaria imperialis L.) using high-throughput sequencing.Molecular biology reports · 2022Article
- Small RNAs, Degradome, and Transcriptome Sequencing Provide Insights into Papaya Fruit Ripening Regulated by 1-MCP.Foods (Basel, Switzerland) · 2021Article
- On humans and their crops-miRNAs and the evolution of fertility.Protoplasma · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Wheat contains the largest number of miR396 family with 17 miR396 in Poaceae. MiR396 regulatory network underlying wheat grain development has not comprehensively been explored. Our results showed that precursor miR396 family in Poaceae exhibited not only conservativeness but also diversification especially in wheat. Five haplotypes were detected in Poaceae species, while 4 haplotypes in wheat with Hap-4 (miR396a) and Hap-5 (miR396n) unique to wheat. GO enrichment analysis of target genes showed that the first 20 enrichment functions of miR396a and miR396n are completely different from each other, and also completely different from miR396(b-g), miR396(h-m), and miR396(o-q). Functional annotation on the 18 target genes shared by miR396(b-g), miR396(h-m), and miR396(o-q) found that 11 of the 18 target genes are growth-regulating factor (GRF) genes. Our results indicated that, during the grain filling stage of wheat, miR396 is involved in the development of grains by regulating the expression of GRF genes (GRF1, GRF6, and GRF9). Although the enrichment function of miR396(b-g), miR396(h-m), and miR396(o-q) is the same, the gene functional networks they formed differ greatly. Our results indicated that polyploidization enriches not only the diversity of miR396 family and its target genes but also gene functional networks in wheat. These results laid foundation for further elucidating function of miR396 gene family underlying wheat grain development.
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