Evidence map›Paper›PMID 32929626›Full record

ArticleWorld journal of urology2021

Ejaculation-sparing thulium laser enucleation of the prostate (ES-ThuLEP): outcomes on a large cohort.

Giorgio Bozzini, Lorenzo Berti, Matteo Maltagliati, Umberto Besana, Alberto Calori, Alexander Müller, Maria Chiara Sighinolfi, Salvatore Micali, Antonio Luigi Pastore, Rodrigo Ledezma and 3 more

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In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

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  3. [Impact of thulium laser enucleation of the prostateBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
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  12. Long Live Holmium!European urology open science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Giorgio BozziniDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy. gioboz@yahoo.it.ORCID http://orcid.org/0000-0001-6274-314X
Lorenzo BertiDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy.
Matteo MaltagliatiDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy.
Umberto BesanaDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy.
Alberto CaloriDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy.
Alexander MüllerDepartment of Urology, Spital Limmattal, Schlieren, Switzerland.
Maria Chiara SighinolfiDepartment of Urology, Università degli Studi di Modena e Reggio Emilia (MO), Modena, Italy.
Salvatore MicaliDepartment of Urology, Università degli Studi di Modena e Reggio Emilia (MO), Modena, Italy.
Antonio Luigi PastoreDepartment of Urology, Sapienza Università di Roma, Latina, Italy.
Rodrigo LedezmaDepartment of Urology, Hospital Clìnico Universidad de Chile, Santiago, Chile.
Paolo BrogginiDepartment of Urology, Clinica Sant'Anna, Lugano, Switzerland.
Bernardo RoccoDepartment of Urology, Università degli Studi di Modena e Reggio Emilia (MO), Modena, Italy.
Carlo BuizzaDepartment of Urology, ASST Valle Olona, Ospedale di Busto Arsizio (VA), Busto Arsizio, Italy.
University of Modena and Reggio Emilia · ITOspedale di Circolo di Busto Arsizio · ITClinica Luganese Moncucco · CHHospital Clínico de la Universidad de Chile · CLSapienza University of Rome · ITSpital Limmattal · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the effects of a new ejaculation-sparing thulium laser enucleation of the prostate (ES-ThuLEP) technique on sexual functions and micturition, in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH) and to evaluate how the surgical technique of ES-ThuLEP can lead to ejaculation preservation.

methodsA prospective study was carried out between January 2015 and January 2018 on patients with surgical indication for BPH, who wished to preserve ejaculation. The patients were treated with ES-ThuLEP and were evaluated before and 3 and 6 months after surgery. Three validated questionnaires (ICIQ-MLUTSsex, IIEF-5 and IPSS) were used to assess changes in ejaculation, erectile function and urinary symptoms. Uroflowmetry (Qmax and Qavg), post-void residual volume and voided volume were also evaluated, to assess micturition improvement. Patients with moderate to severe erectile dysfunction were excluded. Statistical analysis was performed with the Student's t test, Chi-square test and logistic regression analysis.

resultsTwo hundred and eighty three patients were enrolled. Ejaculation was spared in 203 and 219 patients at 3 and 6 months after surgery. No significant differences were observed between erectile function before and after surgery: baseline IIEF-5 = 16.2 ± 4.47 vs 16.7 ± 2.9 (p = 0.419) and 17.7 ± 3.2 (p = 0.410) at 3 and 6 months. Significant improvement in urinary symptoms was achieved: baseline IPSS = 19.4 ± 7.24 vs 5.8 ± 4.3 (p = 0.032) and 3.9 ± 4.1 (p = 0.029) at 3 and 6 months.

conclusionES-ThuLEP effectively preserved ejaculation in over two thirds of the patients without compromising micturition improvement or erectile function. ES-ThuLEP could be a valid treatment option for BPH in young and sexually active men.

Indexed as

EjaculationAgedHumansLaser TherapyLower Urinary Tract SymptomsMaleMiddle AgedProspective StudiesProstatectomyProstatic HyperplasiaThuliumTreatment OutcomeThuliumBenign prostatic hyperplasiaEjaculationEjaculation sparingEjaculatory dysfunctionEndoscopic enucleation of the prostateLower urinary tract symptomsThuLEPThulium laser

Identifiers

PMID32929626
OpenAlexW3085009142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.