ArticleAnnals of biomedical engineering2020
Wall Shear Stress Topological Skeleton Independently Predicts Long-Term Restenosis After Carotid Bifurcation Endarterectomy.
Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 55 citations in OpenAlex.
- Data driven approach to identify vulnerable plaques in carotid atherosclerosis using computed tomography imaging and computational fluid dynamics: A pilot study.PLOS digital health · 2026Article
- Influence of wall distensibility on local hemodynamics at the normal carotid bifurcation: a fluid-structure interaction study.Biomechanics and modeling in mechanobiology · 2026Article
- Uncertainty Quantification in Hemodynamic Metrics from 4D Flow MRI with Super-resolution in a Carotid Bifurcation Model.Journal of imaging informatics in medicine · 2026Article
- In Silico, Patient-Specific Assessment of Local Hemodynamic Predictors and Neointimal Hyperplasia Localisation in an Arteriovenous Graft.Annals of biomedical engineering · 2025Article
- A new understanding of coronary curvature and haemodynamic impact on the course of plaque onset and progression.Royal Society open science · 2024Article
- Predicting Lipid-Rich Plaque Progression in Coronary Arteries Using Multimodal Imaging and Wall Shear Stress Signatures.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Blood Flow Energy Identifies Coronary Lesions Culprit of Future Myocardial Infarction.Annals of biomedical engineering · 2024Article
- Rapid prediction of wall shear stress in stenosed coronary arteries based on deep learning.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Wall shear stress and pressure patterns in aortic stenosis patients with and without aortic dilation captured by high-performance image-based computational fluid dynamics.PLoS computational biology · 2023Article
- Wall shear stress and its role in atherosclerosis.Frontiers in cardiovascular medicine · 2023Review
- Computational Fluid Dynamics (CFD) For Predicting Pathological Changes In The Aorta: Is It Ready For Clinical Use?Arquivos brasileiros de cardiologia · 2022Article
- Utility of vector flow mapping technology in quantitative assessment of carotid wall shear stress in hypertensive patients: A preliminary study.Frontiers in cardiovascular medicine · 2022Article
- Medical Image-Based Computational Fluid Dynamics and Fluid-Structure Interaction Analysis in Vascular Diseases.Frontiers in bioengineering and biotechnology · 2022Review
- A distributed lumped parameter model of blood flow with fluid-structure interaction.Biomechanics and modeling in mechanobiology · 2021Article
- Early Atherosclerotic Changes in Coronary Arteries are Associated with Endothelium Shear Stress Contraction/Expansion Variability.Annals of biomedical engineering · 2021Article
- On the Potential Self-Amplification of Aneurysms Due to Tissue Degradation and Blood Flow Revealed From FSI Simulations.Frontiers in physiology · 2021Article
- Effects of the Haemodynamic Stimulus on the Location of Carotid Plaques Based on a Patient-Specific Mechanobiological Plaque Atheroma Formation Model.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Wall Shear Stress (WSS) topological skeleton, composed by fixed points and the manifolds linking them, reflects the presence of blood flow features associated to adverse vascular response. However, the influence of WSS topological skeleton on vascular pathophysiology is still underexplored. This study aimed to identify direct associations between the WSS topological skeleton and markers of vascular disease from real-world clinical longitudinal data of long-term restenosis after carotid endarterectomy (CEA). Personalized computational hemodynamic simulations were performed on a cohort of 13 carotid models pre-CEA and at 1 month after CEA. At 60 months after CEA, intima-media thickness (IMT) was measured to detect long-term restenosis. The analysis of the WSS topological skeleton was carried out by applying a Eulerian method based on the WSS vector field divergence. To provide objective thresholds for WSS topological skeleton quantitative analysis, a computational hemodynamic dataset of 46 ostensibly healthy carotid bifurcation models was considered. CEA interventions did not completely restore physiological WSS topological skeleton features. Significant associations emerged between IMT at 60 months follow-up and the exposure to (1) high temporal variation of WSS contraction/expansion (R
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.