Evidence map›Paper›PMID 32929532›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

Pediatric kidney transplantation in China: an analysis from the IPNA Global Kidney Replacement Therapy Registry.

Qian Shen, Xiaoyan Fang, Xinyue Man, Yihui Zhai, Longshan Liu, Changxi Wang, Wenjun Shang, Guiwen Feng, Lei Zhang, Li Zeng and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Pediatric Organ Transplantation in China.Pediatric transplantation · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genetic spectrum of CAKUT and risk factors for kidney failure: a pediatric multicenter cohort study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qian Shen *Department of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Xiaoyan Fang *Department of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Xinyue ManDepartment of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Yihui ZhaiDepartment of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Longshan LiuOrgan Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Changxi WangOrgan Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wenjun ShangDepartment of Kidney Transplantation, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guiwen FengDepartment of Kidney Transplantation, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lei ZhangDepartment of Organ Transplantation, Changhai Hospital, Second Military Medical University, Shanghai, China.
Li ZengDepartment of Organ Transplantation, Changhai Hospital, Second Military Medical University, Shanghai, China.
Youhua ZhuDepartment of Organ Transplantation, Changhai Hospital, Second Military Medical University, Shanghai, China.
Jing ChenDepartment of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Jia RaoDepartment of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Bradley A WaradyDivision of Pediatric Nephrology, Children's Mercy Kansas City, Kansas City, MO, USA.
Franz SchaeferPediatric Nephrology Division, Heidelberg University Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany.
Hong XuDepartment of Nephrology, Children's Hospital of Fudan University, Shanghai, China. hxu@shmu.edu.cn.ORCID 0000-0001-7617-0872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe International Pediatric Nephrology Association (IPNA) Global Kidney Replacement Therapy (KRT) Registry was established to evaluate the incidence and outcomes of kidney replacement therapy (dialysis and transplantation) provided to children worldwide. Analysis of registry data for separate regions is feasible.

methodsThree centers located in Shanghai, Guangzhou, and Zhengzhou, which have the greatest number of pediatric kidney transplantation cases in China, participated in this analysis of transplant data. Data were registered by each center for patients under the age of 19 years who received a single-organ kidney transplant for the first time between 2011 and 2018.

resultsIn total, 415 patients (59.8% male) aged 1.4-18.7 (median 12.1) years were followed for 0.3-97.1 (median 27.7) months. The number of kidney transplants increased from a total of 129 during 2011-2014 to 286 cases during 2015-2018. 85.8% of patients received the transplanted kidney from a pediatric (age < 19 years) donor, and deceased donors accounted for 94% of all donors. 8.0% of grafts were lost. One and 5-year patient survival rates were 97.6% and 95.5%, respectively. The major cause of death was infection (7/14). Similar graft and patient survival rates were observed for organs from pediatric and adult donors in 6-11 and 12-18 year recipient age groups, whereas recipients < 6 years showed inferior patient and graft survival.

conclusionsPediatric kidney transplantation shows favorable short-term and medium-term outcomes in China. Our experience supports use of pediatric donors in pediatric kidney transplantation, but attention directed to the outcome of recipients aged under 6 is necessary. Graphical abstract.

Indexed as

Kidney TransplantationAdolescentChildChinaFemaleGraft SurvivalHumansMaleNephrologyRegistriesRenal DialysisTissue DonorsTreatment OutcomeYoung AdultChildrenChinaKidney transplantPrognosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.