Evidence map›Paper›PMID 32929524›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021

Males Have Higher Rates of Peri-operative Mortality Following Surgery for Osteoporotic Vertebral Compression Fracture.

A Gupta, T Cha, J Schwab, H Fogel, D Tobert, S Cho, A Hecht, C M Bono, S Hershman

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Assessing impacts of gender on adverse postoperative outcomes in patients undergoing osteoporotic vertebral compression fracture surgery.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  4. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

A GuptaDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
T ChaDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
J SchwabDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
H FogelDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
D TobertDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
S ChoDepartment of Orthopaedics, Icahn School of Medicine at Mount Sinai, The Mount Sinai Hospital, Mount Sinai Hospital, 425 West 59th St., New York, NY, 10019, USA.
A HechtDepartment of Orthopaedics, Icahn School of Medicine at Mount Sinai, The Mount Sinai Hospital, Mount Sinai Hospital, East 98th St., New York, NY, 10029, USA.
C M BonoDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA.
S HershmanDepartment of Orthopaedics, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, MA, 02114, Boston, USA. shhershman@mgh.harvard.edu.
Massachusetts General Hospital · USHarvard University · USIcahn School of Medicine at Mount Sinai · USMount Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we evaluated the association between sex and the incidence of postoperative mortality in the peri-operative period following surgical intervention for OVCF. We found no statistical association between surgical complications and patient sex. However, males exhibited higher rates of mortality and 30-day readmissions relative to females.

introductionOsteoporotic vertebral compression fractures (OVCF) contribute substantially to the financial burden of the US healthcare system. As the size of the elderly population grows, the number of fractures attributed to osteoporosis is expected to increase. Studies have shown that osteoporotic patients are at an increased risk for medical and surgical complications. The purpose of this study was to evaluate the association between sex and the incidence of postoperative mortality in the peri-operative period following surgical intervention for OVCF.

methodsA retrospective analysis of the American College of Surgeons National Surgery Quality Improvement Project (ACS-NSQIP) database from 2007 to 2014 identified 1979 patients. Patients were grouped as male or female. Mortality within 30 days of surgery due to any cause, incidence of surgical complications, and 30-day readmission rates following surgery were tabulated. A multivariate logistic regression analysis was conducted to calculate odds ratios (OR) with corresponding p values and 95% confidence intervals.

resultsIn total, 1979 patients met inclusion and exclusion criteria. Mortality within the 30 days following surgery for OVCF was statistically greater in men than in women (OR = 1.58; p = 0.050). The 30-day readmission rate was also statistically higher in men (OR = 1.41; p = 0.017). Neither minor (OR = 0.90; p = 0.560) nor major (OR = 1.14; p = 0.569) complications were statistically correlated with sex. On average, men underwent surgery for OVCF at a younger age than women.

conclusionsMale patients undergoing surgery for OVCF have higher rates of peri-operative mortality and 30-day readmissions following surgery. Sex was not found to be associated with postoperative complications. LEVEL OF EVIDENCE: III.

Indexed as

Fractures, CompressionOsteoporotic FracturesSpinal FracturesAgedFemaleHumansMalePatient ReadmissionPostoperative ComplicationsRetrospective StudiesAdverse outcomesGenderMortalitySexSpineVertebral compression fracture

Identifiers

PMID32929524
OpenAlexW3086179324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.